Version 1
: Received: 13 July 2021 / Approved: 14 July 2021 / Online: 14 July 2021 (15:19:40 CEST)
How to cite:
Poon, C.; Rinehart, B.; Langri, D.S.; Rambo, T.M.; Miller, A.J.; Foreman, B.; Sunar, U. Noninvasive Optical Monitoring of Cerebral Blood Flow and EEG Spectral Responses after Severe Traumatic Brain Injury: A Case Report. Preprints2021, 2021070340. https://doi.org/10.20944/preprints202107.0340.v1
Poon, C.; Rinehart, B.; Langri, D.S.; Rambo, T.M.; Miller, A.J.; Foreman, B.; Sunar, U. Noninvasive Optical Monitoring of Cerebral Blood Flow and EEG Spectral Responses after Severe Traumatic Brain Injury: A Case Report. Preprints 2021, 2021070340. https://doi.org/10.20944/preprints202107.0340.v1
Poon, C.; Rinehart, B.; Langri, D.S.; Rambo, T.M.; Miller, A.J.; Foreman, B.; Sunar, U. Noninvasive Optical Monitoring of Cerebral Blood Flow and EEG Spectral Responses after Severe Traumatic Brain Injury: A Case Report. Preprints2021, 2021070340. https://doi.org/10.20944/preprints202107.0340.v1
APA Style
Poon, C., Rinehart, B., Langri, D.S., Rambo, T.M., Miller, A.J., Foreman, B., & Sunar, U. (2021). Noninvasive Optical Monitoring of Cerebral Blood Flow and EEG Spectral Responses after Severe Traumatic Brain Injury: A Case Report. Preprints. https://doi.org/10.20944/preprints202107.0340.v1
Chicago/Turabian Style
Poon, C., Brandon Foreman and Ulas Sunar. 2021 "Noninvasive Optical Monitoring of Cerebral Blood Flow and EEG Spectral Responses after Severe Traumatic Brain Injury: A Case Report" Preprints. https://doi.org/10.20944/preprints202107.0340.v1
Abstract
Survivors of severe brain injury may require care in a neurointensive care unit (neuro-ICU), where the brain is vulnerable to secondary brain injury. Thus, there is a need for noninvasive, bedside, continuous cerebral blood flow monitoring approaches in the neuro-ICU. Our goal is to address this need through combined measurements of EEG and functional optical spectroscopy (EEG-Optical) instrumentation and analysis to provide a complementary fusion of data about brain activity and function. The present case demonstrates in a patient with traumatic brain injury, noninvasive cerebral blood flow transients can be recorded that correlate with gold-standard invasive measurements and with the frequency content changes in the EEG data during clinical care.
Keywords
cerebral blood flow and oxygenation; diffuse correlation spectroscopy; EEG; traumatic brain in-jury; neurointensive care unit; neuromonitoring
Subject
Medicine and Pharmacology, Immunology and Allergy
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.