Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

CRISPR Cas9 Tip of an Iceberg: It’s Potential in Genome Editing and Many More

Version 1 : Received: 6 July 2021 / Approved: 8 July 2021 / Online: 8 July 2021 (09:50:22 CEST)

How to cite: Ahmad, J.; Siddique, N. CRISPR Cas9 Tip of an Iceberg: It’s Potential in Genome Editing and Many More. Preprints 2021, 2021070182 (doi: 10.20944/preprints202107.0182.v1). Ahmad, J.; Siddique, N. CRISPR Cas9 Tip of an Iceberg: It’s Potential in Genome Editing and Many More. Preprints 2021, 2021070182 (doi: 10.20944/preprints202107.0182.v1).

Abstract

Clustered regularly interspaced short palindromic repeats or CRISPR, one of the major technological tools from nature's toolbox, has revolutionized the scientific world with its potential use in humans and plants. CRISPR Cas9 was first known as an adaptive immune system of bacteria. It is a system that cleaves foreign DNA. It has been exploited to be used as a genome editing tool for correcting genetic diseases in humans, for plants to create stress-resistant plants, and for a variety of different purposes. This review provides a basic overview of its applications in different areas of biological research. It has immense potential for a variety of researches, but it's still a mystery for science. It feels like scientists just know a tip of an iceberg.

Subject Areas

CRISPR-Cas9; Genome editing; plant editing; bacterial immune system; genetic disease

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