Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

A Review on Green Synthesis and Biological Activities of Nitrogen and Oxygen Containing Heterocycles

Version 1 : Received: 11 June 2021 / Approved: 14 June 2021 / Online: 14 June 2021 (10:39:56 CEST)

How to cite: Gulati, S.; Singh, R.; Sangwan, S. A Review on Green Synthesis and Biological Activities of Nitrogen and Oxygen Containing Heterocycles. Preprints 2021, 2021060350 (doi: 10.20944/preprints202106.0350.v1). Gulati, S.; Singh, R.; Sangwan, S. A Review on Green Synthesis and Biological Activities of Nitrogen and Oxygen Containing Heterocycles. Preprints 2021, 2021060350 (doi: 10.20944/preprints202106.0350.v1).

Abstract

Heterocycles are unique precursors for the synthesis of various pharmaceuticals and agrochemicals particularly those possessing N- or O- moieties. The development of methods to prepare heterocycles is of great importance in synthesis of organic compounds, especially the heterocycles which can be found in natural products. The synthesis of nitrogen and oxygen containing heterocycles viz. coumarins, dihydropyrimidinones, imidazoles, isoxazoles and benzimidazoles represented an attractive and demanding work for chemists as these nucleus has found extensive applications in several fields such as material science, analytical chemistry and most importantly in medicinal chemistry. Organic synthesis has been attracted towards the development of new environmental friendly procedures to achieve the goals of green chemistry. The fundamental aspects of green chemistry are use of biocatalysts and environmental benign solvents under mild conditions. The present review article summarized the green synthetic methods and biological activities of nitrogen and oxygen containing heterocycles.

Subject Areas

Heterocycles; Coumarins; Dihyfropyrimidinones; Imidazoles; Isoxazoles; Benzimidazoles; Green Chemistry

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