Preprint Review Version 2 Preserved in Portico This version is not peer-reviewed

Elastomer-Hydrogel Systems: From Bio-Inspired Interfaces to Medical Applications

Version 1 : Received: 30 May 2021 / Approved: 1 June 2021 / Online: 1 June 2021 (11:18:20 CEST)
Version 2 : Received: 19 April 2022 / Approved: 20 April 2022 / Online: 20 April 2022 (11:39:28 CEST)

How to cite: El Fray, M.; Demirci, G.; Niedźwiedź, M.; Kantor-Malujdy, N. Elastomer-Hydrogel Systems: From Bio-Inspired Interfaces to Medical Applications. Preprints 2021, 2021060026 (doi: 10.20944/preprints202106.0026.v2). El Fray, M.; Demirci, G.; Niedźwiedź, M.; Kantor-Malujdy, N. Elastomer-Hydrogel Systems: From Bio-Inspired Interfaces to Medical Applications. Preprints 2021, 2021060026 (doi: 10.20944/preprints202106.0026.v2).

Abstract

Novel advanced biomaterials have recently gained great attention, especially in surgical minimally invasive techniques. Applying sophisticated design and engineering methods, various elastomer-hydrogel systems (EHS) with outstanding performance have been developed in last decades. Those systems composed of elastomers and hydrogels are very attractive due to their high biocompatibility, injectability, controlled porosity and often antimicrobial properties. Moreover, elastomeric properties and bioadhesiveness are making them suitable for soft tissue engineering. Herein, we present the advances in current state-of-the-art design principles and strategies for strong interface formation inspired by nature (bio-inspiration), diverse properties and applications of elastomer-hydrogel systems in different medical fields, in particular, in tissue engineering. Functionalities of those systems, including adhesive properties, injectability, antimicrobial properties and degradability applicable to tissue engineering will be discussed in a context of future efforts towards development of advanced biomaterials.

Keywords

elastomers; hydrogels; elastomer-hydrogel systems; injectable biomaterials; adhesive surfaces; tissue engineering

Subject

MATERIALS SCIENCE, Biomaterials

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