Why Recessive Lethal Alleles Have Not Disappeared?

Jorma Jormakka; Sourangshu Ghosh

doi:10.20944/preprints202105.0751.v1

Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 28 May 2021 / Approved: 31 May 2021 / Online: 31 May 2021 (11:37:33 CEST)

The article derives the probability for lethal recessive alleles in the case of recessive disadvantage or advantage. It is shown that the recessive advantage of a lethal gene can be detected by the ratio of heterozygotes and homozygotes. This demonstrates that the higher IQ of certain ethnic groups cannot be explained by the recessive advantage of lethal genes. The article shows that lethal genes can survive in the population if some lineages of families have much more children than the average.

Recessive Alleles; Heterozygote advantage; Lethal Genes

Biology and Life Sciences, Biochemistry and Molecular Biology

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Why Recessive Lethal Alleles Have Not Disappeared?

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