Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Why Recessive Lethal Alleles Have Not Disappeared?

Version 1 : Received: 28 May 2021 / Approved: 31 May 2021 / Online: 31 May 2021 (11:37:33 CEST)

How to cite: Jormakka, J.; Ghosh, S. Why Recessive Lethal Alleles Have Not Disappeared?. Preprints 2021, 2021050751 (doi: 10.20944/preprints202105.0751.v1). Jormakka, J.; Ghosh, S. Why Recessive Lethal Alleles Have Not Disappeared?. Preprints 2021, 2021050751 (doi: 10.20944/preprints202105.0751.v1).

Abstract

The article derives the probability for lethal recessive alleles in the case of recessive disadvantage or advantage. It is shown that the recessive advantage of a lethal gene can be detected by the ratio of heterozygotes and homozygotes. This demonstrates that the higher IQ of certain ethnic groups cannot be explained by the recessive advantage of lethal genes. The article shows that lethal genes can survive in the population if some lineages of families have much more children than the average.

Subject Areas

Recessive Alleles; Heterozygote advantage; Lethal Genes

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