Persistence of Anti-SARS-CoV-2 Antibodies Six Months After Infection in an Outbreak With Five Hundred COVID-19 Cases in Borriana (Spain): A Prospective Cohort Study

Comment: Editor of Preprint
Dear Ms. Milena Amidzic:
In our manuscript published in Preprint ID:preprints-43361
 “Persistence of Anti-SARS-CoV-2 Antibodies Six Months After Infection in an Outbreak With Five Hundred COVID-19 Cases in Borriana (Spain): A Prospective Cohort Study”. Authors: Domènech-Montoliu, S.; Puig-Barberà, J.; Pac-Sa, M.R.; Vidal-Utrillas, P.; Latorre-Poveda, M.; Del Rio-González, A.; Ferrando-Rubert, S.; Ferrer-Abad, G.; Sánchez-Urbano, M.; Aparisi-Esteve, L.; Badenes-Marques, G.; Cervera-Ferrer, B.; Clerig-Arnau, U.; Dols-Bernad, C.; Fontal-Carcel, M.; Gomez-Lanas, L.; Jovani-Sales, D.; León-Domingo, M.C.; Llopico-Vilanova, M.D.; Moros-Blasco, M.; Notari-Rodríguez, C.; Ruíz-Puig, R.; Valls-López, S.; Arnedo-Pena, A Version 1 : Received: 20 May 2021 / Approved: 21 May 2021 / Online: 21 May 2021 (15:41:51 CEST).

There is a typo in relation to the Ethics committee of the Hospital de la Plana Vila-real, and we could like to make a modification in the material and methods, and the Institutional Review Board Statement of our manuscript. The new paragraphs are the following:
Material and Methods:
The following of the study’s cohort was a part of the public health surveillance as a prolongation of the COVID-19 outbreak control measures and the response of the COVID-19 pandemic. It was exempt from the Ethics Review Board approval’s protocol according to the Spanish legislation. The study was approved by the director of the Public Health Center of Castellón and the management of the Health Department of la Plana. All participants or the parents of minors provided the informed written consent to be included in the study.

Institutional Review Board Statement:
The study of this cohort was a part of the public health surveillance as a prolongation of the COVID-19 outbreak in the Falles festival of Borriana control measures (1) and was exempt from the Ethics Review Board approval’s protocol according to the Spanish legislation, including the General Low including the General Law of Health (2), the Law of Cohesion and Quality of the National System of Health (3), and the Law General of Public Health (4). In addition, the cohort was followed to respond to a new disease, the COVID-19 pandemic (5).          

1. Domènech-Montoliu S, Pac-Sa MR, Vidal-Utrillas P, Latorre-Poveda M, Del Rio-González A, Ferrando-Rubert S, et al. "Mass gathering events and COVID-19 transmission in Borriana (Spain): A retrospective cohort study". PLoS One. 2021 Aug 26;16(8):e0256747. doi: 10.1371/journal.pone.0256747.

2.Ley 16/2003, de 28 de mayo, de cohesión y calidad del Sistema Nacional de Salud. (Law of Cohesion and Quality of the National System of Health).  https://www.boe.es/eli/es/l/2003/05/28/16 Access: 2 August 2021.

3.Ley 33/2011, de 4 de octubre, General de Salud Pública (Law General of Public Health).  https://www.boe.es/eli/es/l/2011/10/04/33/con Access: 2 August 2021.2.    

4.Ley 14/1986, de 25 de abril, General de Sanidad (Law General of Health):  https://www.boe.es/eli/es/l/1986/04/25/14/con  Access: 2 August 20215. 
5.Ministerio de Sanidad Acordado en Consejo Interterritorial del Sistema Nacional de Salud el 16 de julio de 2020. Plan de respuesta temprana en un escenario de control de la pandemia por el COVID-19.pdf (Ministry of Health Agreed in the Interterritorial Council of the National Health System on July 16, 2020”. Early response plan in a COVID-19 pandemic control scenario. pdf).
We hope that this modification could be feasible and convenient. We are very satisfied with the Preprint edition of our study and appreciate your attention to our research.
Best wishes from Castelló de la PlanaDr.
Alberto Arnedo-Pena, on behalf of the authors.