Preprint Hypothesis Version 3 Preserved in Portico This version is not peer-reviewed

Rethinking Life and Predicting Its Origin

Version 1 : Received: 9 May 2021 / Approved: 11 May 2021 / Online: 11 May 2021 (10:40:20 CEST)
Version 2 : Received: 14 May 2021 / Approved: 17 May 2021 / Online: 17 May 2021 (09:46:37 CEST)
Version 3 : Received: 15 June 2021 / Approved: 16 June 2021 / Online: 16 June 2021 (11:30:35 CEST)

How to cite: Gonçalves, D. Rethinking Life and Predicting Its Origin. Preprints 2021, 2021050234. Gonçalves, D. Rethinking Life and Predicting Its Origin. Preprints 2021, 2021050234.


The definition, origin and recreation of life remain elusive. As others have suggested, only once we put life into reductionist physical terms will we be able to solve those questions. To that end, this work proposes the phenomenon of life to be the product of two dissipative mechanisms. From them, one reinterprets extant biological life and deduces a testable scenario for its origin. The proposed theory of life allows its replication, reinterprets ecological evolution, creates new constraints on the search for life and lays the foundations for groundbreaking technologies.


Theory of Life; Definition of Life; Origin of Life; Electron Bifurcation; Hydrothermal Vents; Biophysics; Biological Physics


Physical Sciences, Applied Physics

Comments (1)

Comment 1
Received: 16 June 2021
Commenter: Diogo Gonçalves
Commenter's Conflict of Interests: Author
Comment: It was clarified that the 1st Principle is commonly interpreted as the undergoing of “entropy-destroying” chemical processes, and the 2nd Principle is embodied by metabolic regulation mechanisms. Other minor issues were addressed throughout the manuscript. The citation style was changed.
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