Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Cropping up Crisis at the Nexus Between COVID-19 and AMR in Africa: A Scoping Review and Synthesis of Early Evidence

Version 1 : Received: 6 May 2021 / Approved: 7 May 2021 / Online: 7 May 2021 (16:21:37 CEST)

How to cite: Gutema, G.; Homa, G. Cropping up Crisis at the Nexus Between COVID-19 and AMR in Africa: A Scoping Review and Synthesis of Early Evidence. Preprints 2021, 2021050152 (doi: 10.20944/preprints202105.0152.v1). Gutema, G.; Homa, G. Cropping up Crisis at the Nexus Between COVID-19 and AMR in Africa: A Scoping Review and Synthesis of Early Evidence. Preprints 2021, 2021050152 (doi: 10.20944/preprints202105.0152.v1).

Abstract

Objective In this study, we aim to synthesize some evidence on the impacts that COVID-19 is having on the epidemiology of Antimicrobial Resistance (AMR) in Africa since it was declared global pandemic by WHO in March 2020. Methodology A scoping review was undertaken by collecting and curating relevant resources from peer-reviewed articles and also from the gray literature. Mixed approaches of extracting data (qualitative and quantitative) were employed in synthesizing evidence, as suggested by Health Evidence Network (HEN). Findings A model constructed based on the synthesis of early evidences available on the effects of factors linked to COVID-19 in impacting the evolution of AMR in Africa predicted that, in cumulative terms, those factors favoring the evolution of AMR outpace those disfavoring it by no less than three folds. Conclusion COVID-19 is fueling the evolution of AMR almost unhindered in Africa. Due recognition of this crisis, concerted efforts for resource mobilization and global cooperation are needed to tackle it.

Keywords

COVID-19 impacts; Antimicrobial resistance; Africa

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