Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Drinks and Food Caffeine Consumption and Factors Associated With Higher Intakes. A Cohort Study In Pregnant Women

Version 1 : Received: 19 April 2021 / Approved: 20 April 2021 / Online: 20 April 2021 (11:08:10 CEST)

How to cite: Román-Gálvez, M.R.; Hernández-Martínez, L.; Amezcua-Prieto, C.; Cano-Ibañez, N.; Olmedo-Requena, R.; Martínez-Galiano, J.M.; Bueno-Cavanillas, A. Drinks and Food Caffeine Consumption and Factors Associated With Higher Intakes. A Cohort Study In Pregnant Women. Preprints 2021, 2021040527 (doi: 10.20944/preprints202104.0527.v1). Román-Gálvez, M.R.; Hernández-Martínez, L.; Amezcua-Prieto, C.; Cano-Ibañez, N.; Olmedo-Requena, R.; Martínez-Galiano, J.M.; Bueno-Cavanillas, A. Drinks and Food Caffeine Consumption and Factors Associated With Higher Intakes. A Cohort Study In Pregnant Women. Preprints 2021, 2021040527 (doi: 10.20944/preprints202104.0527.v1).

Abstract

We aimed to assess the caffeine intake before and during pregnancy, compliance with caffeine recommendations during pregnancy (200 mg/day) and factors associated with higher intakes before and in first trimester of pregnancy. Caffeine consumption was collected in a Spanish cohort of pregnant women through a validated food questionnaire, before and in each trimester of gestation (T1, T2 and T3). 463 pregnant women were recruited and follow-up through pregnancy. Compliance with caffeine intake recommendations during pregnancy and quintiles of mg/day of caffeine before and in T1 of pregnancy were calculated. A multivariate logistic regression, comparing extreme quintiles of consumption (Q1 vs Q5) was used. Mean caffeine intake before pregnancy was 120.05 mg/day (SD 117.85), 42.76 mg/day (SD 63.90) at 12th GW, 42.00 mg/day (SD 59.76) at 24th GW and 39.34 mg/day (SD 50.9) at 32nd GW (p<0.001). 86% of women complied with caffeine recommendations during pregnancy. At pregnancy (T1), being an active smoker was associated with Q5 > 100.1 mg/day, aOR = 22.69; 95% CI 4.67- 110.26. igh diet quality, aOR = 0.30; 95% CI, 0.13- 0.68, and moderate physical activity level, aOR= 0.44; 95% CI, 0.19-1.00, were inversely associated with Q5 > 100.1 mg/day. Pregnant women are mostly adhering to current caffeine intake guidelines. Higher caffeine intake at pregnancy is associated with other unhealthy habits during pregnancy.

Subject Areas

caffeine, pre-pregnancy, pregnancy, intake, quintiles

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