Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Alcoholism as a Risk Factor for COVID-19: Boosting Inflammatory Response

Version 1 : Received: 19 March 2021 / Approved: 22 March 2021 / Online: 22 March 2021 (15:45:51 CET)

How to cite: Akram, M.; Iqbal, M.; Altable, M.; de la Serna, J.M. Alcoholism as a Risk Factor for COVID-19: Boosting Inflammatory Response. Preprints 2021, 2021030547 (doi: 10.20944/preprints202103.0547.v1). Akram, M.; Iqbal, M.; Altable, M.; de la Serna, J.M. Alcoholism as a Risk Factor for COVID-19: Boosting Inflammatory Response. Preprints 2021, 2021030547 (doi: 10.20944/preprints202103.0547.v1).

Abstract

Alcoholism is a condition associated with psychiatric and psychiatric problems, where the respiratory system is damaged through the mucociliary ladder mechanism and alveolar macrophage dysfunction. In the time COVID-19 has been observed a dramatic increase in alcohol consumption mediated by levels of anxiety and situations of confinement. In this work we analyze the relationship between alcoholism and SARS, especially with SARS-CoV-2, explained by a degradation of the host defenses of the respiratory epithelium by changing the barrier function, the discharge of cytokines and the functions of the cilia. All of them involved in the defense mechanism. of the lungs. This leads to a worse prognosis for patients precisely because of alcohol consumption. Based on this approach, alcoholism will exacerbate the consequences of COVID-19.

Subject Areas

Alcohol; cytokine; proinflammatory; COVID-19; SARS-CoV-2

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