Working Paper Article Version 1 This version is not peer-reviewed

Deep Neural Networks for Analysis of Microscopy Images - Synthetic Data Generation and Adaptive Sampling

Version 1 : Received: 27 February 2021 / Approved: 1 March 2021 / Online: 1 March 2021 (13:07:00 CET)

A peer-reviewed article of this Preprint also exists.

Journal reference: Crystals 2021, 11, 258
DOI: 10.3390/cryst11030258


The analysis of microscopy images has always been an important yet time consuming process in in materials science. Convolutional Neural Networks (CNNs) have been very successfully used for a number of tasks, such as image segmentation. However, training a CNN requires a large amount of hand annotated data, which can be a problem for material science data. We present a procedure to generate synthetic data based on ad-hoc parametric data modelling for enhancing generalization of trained neural network models. Especially for situations where it is not possible to gather a lot of data, such an approach is beneficial and may enable to train a neural network reasonably. Furthermore, we show that targeted data generation by adaptively sampling the parameter space of the generative models gives superior results compared to generating random data points.


Microscopy Image Segmentation; Deep Learning; Data Augmentation; Synthetic Training Data; Parametric Models



Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0

Notify me about updates to this article or when a peer-reviewed version is published.

We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.