Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Phylogenetic Analysis of the 2020 West Nile Virus (WNV) Outbreak in Andalusia (Spain)

Version 1 : Received: 24 February 2021 / Approved: 26 February 2021 / Online: 26 February 2021 (09:46:38 CET)

How to cite: Casimiro-Soriguer, C.S.; Perez-Florido, J.; Fernandez-Rueda, J.L.; Pedrosa-Corral, I.; Guillot-Sulay, V.; Lorusso, N.; Martinez-Gonzalez, L.J.; Navarro-Marí, J.M.; Dopazo, J.; Sanbonmatsu-Gámez, S. Phylogenetic Analysis of the 2020 West Nile Virus (WNV) Outbreak in Andalusia (Spain). Preprints 2021, 2021020604 (doi: 10.20944/preprints202102.0604.v1). Casimiro-Soriguer, C.S.; Perez-Florido, J.; Fernandez-Rueda, J.L.; Pedrosa-Corral, I.; Guillot-Sulay, V.; Lorusso, N.; Martinez-Gonzalez, L.J.; Navarro-Marí, J.M.; Dopazo, J.; Sanbonmatsu-Gámez, S. Phylogenetic Analysis of the 2020 West Nile Virus (WNV) Outbreak in Andalusia (Spain). Preprints 2021, 2021020604 (doi: 10.20944/preprints202102.0604.v1).

Abstract

During the last decades West Nile Virus (WNV) outbreaks have continuously occurred in the Mediterranean area. In August 2020 a new WNV outbreak affected 71 people with meningoencephalitis in Andalusia and 6 more cases in Extremadura (south-west of Spain), causing a total of eight deaths. The whole genomes of four viral isolates were obtained and phylogenetically analyzed in the context of recent outbreaks. The Andalusian viral samples belonged to the lineage 1 and were relatively similar to previous outbreaks occurred in the Mediterranean region. Here we present a detailed analysis of the outbreak, including an extensive phylogenetic study.

Subject Areas

West Nile Virus; outbreak; meningoencephalitis; epidemiology; phylogeny; whole genome sequencing

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