Entamoeba Histolytica - Gut Microbiota Interaction: More Than Meets the Eye

Serge Ankri

Working Paper Review Version 1 This version is not peer-reviewed

Version 1 : Received: 23 February 2021 / Approved: 24 February 2021 / Online: 24 February 2021 (16:26:55 CET)

Amebiasis is a disease caused by the unicellular parasite Entamoeba histolytica. In most cases, the infection is asymptomatic but when symptomatic, the infection can cause dysentery and invasive extraintestinal complications. In the gut, E.histolytica feeds on bacteria. Increasing evidences support the role of the gut microbiota in the development of the disease. In this review we will discuss the consequences of E.histolytica infection on the gut microbiota. We will also discuss new evidences about the role of the gut microbiota in regulating the resistance of the parasite to oxi-dative stress and its virulence.

gut microbiota; Entamoeba histolytica; resistance to oxidative stress; resistance to nitrosative stress; virulence

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Entamoeba Histolytica - Gut Microbiota Interaction: More Than Meets the Eye

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