Agustín, R.-S.; Crisostomo, M.J.; Sánchez-Martínez, M.P.; Medina-Mirapeix, F. Responsiveness and Minimal Clinically Important Difference of the Five Times Sit-to-Stand Test in Patients with Stroke. Int. J. Environ. Res. Public Health2021, 18, 2314.
Agustín, R.-S.; Crisostomo, M.J.; Sánchez-Martínez, M.P.; Medina-Mirapeix, F. Responsiveness and Minimal Clinically Important Difference of the Five Times Sit-to-Stand Test in Patients with Stroke. Int. J. Environ. Res. Public Health 2021, 18, 2314.
Agustín, R.-S.; Crisostomo, M.J.; Sánchez-Martínez, M.P.; Medina-Mirapeix, F. Responsiveness and Minimal Clinically Important Difference of the Five Times Sit-to-Stand Test in Patients with Stroke. Int. J. Environ. Res. Public Health2021, 18, 2314.
Agustín, R.-S.; Crisostomo, M.J.; Sánchez-Martínez, M.P.; Medina-Mirapeix, F. Responsiveness and Minimal Clinically Important Difference of the Five Times Sit-to-Stand Test in Patients with Stroke. Int. J. Environ. Res. Public Health 2021, 18, 2314.
Abstract
This study aimed to analyze the responsiveness of the 5STS test among stroke patients and to estimate the MCIDs for different severity levels of community ambulation and stages of recovery. The 5STS and comparator instruments [gait speed and Functional Ambulatory Category (FAC)] were evaluated at baseline. These measures were repeated at 4 (Stage 1) and 8 weeks (Stage 2), together with the Global Rating of Change (GROC). The MCIDs were calculated with two anchor-based methods using the GROC as the external criterion. Responsiveness to change for the 5STS was estimated analyzing the correlation with changes in the two comparator instruments and their capacity to discriminate improvement. For the 5STS test, while the MCIDs of the limited community ambulators were similar in the two stages (around 3 s), those of the household ambulators decreased from 1.9 s to 0.72 s. Spearman's rho coefficients showed an acceptable correlation between changes in 5STS and changes for both the FAC and gait speed changes in both stages of recovery. Our study revealed that the 5STS is responsive to functional changes in patients with stroke and that their degree of severity and stage of recovery influence the MCID values of the 5STS.
Keywords
5STS; stroke; MCID; responsiveness; stages; severity level; gait speed; FAC
Subject
Medicine and Pharmacology, Immunology and Allergy
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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