Ibrahim S, Wei Hoong L, Lai Siong Y, Mustapha Z, C W Zalati CWS, Aklilu E, Mohamad M, Kamaruzzaman NF. Prevalence of Antimicrobial Resistance (AMR) Salmonella spp. and Escherichia coli Isolated from Broilers in the East Coast of Peninsular Malaysia. Antibiotics (Basel). 2021 May 13;10(5):579. doi: 10.3390/antibiotics10050579. PMID: 34068312; PMCID: PMC8153281.
Ibrahim S, Wei Hoong L, Lai Siong Y, Mustapha Z, C W Zalati CWS, Aklilu E, Mohamad M, Kamaruzzaman NF. Prevalence of Antimicrobial Resistance (AMR) Salmonella spp. and Escherichia coli Isolated from Broilers in the East Coast of Peninsular Malaysia. Antibiotics (Basel). 2021 May 13;10(5):579. doi: 10.3390/antibiotics10050579. PMID: 34068312; PMCID: PMC8153281.
Ibrahim S, Wei Hoong L, Lai Siong Y, Mustapha Z, C W Zalati CWS, Aklilu E, Mohamad M, Kamaruzzaman NF. Prevalence of Antimicrobial Resistance (AMR) Salmonella spp. and Escherichia coli Isolated from Broilers in the East Coast of Peninsular Malaysia. Antibiotics (Basel). 2021 May 13;10(5):579. doi: 10.3390/antibiotics10050579. PMID: 34068312; PMCID: PMC8153281.
Ibrahim S, Wei Hoong L, Lai Siong Y, Mustapha Z, C W Zalati CWS, Aklilu E, Mohamad M, Kamaruzzaman NF. Prevalence of Antimicrobial Resistance (AMR) Salmonella spp. and Escherichia coli Isolated from Broilers in the East Coast of Peninsular Malaysia. Antibiotics (Basel). 2021 May 13;10(5):579. doi: 10.3390/antibiotics10050579. PMID: 34068312; PMCID: PMC8153281.
Abstract
Abstract:Salmonella species (spp) and Escherichia coli(E. coli) are the most common infectious pathogens in poultry. Antimicrobials were given either for the treatment or growth promoters that can increase the possibility of emergence of bacterial resistance towards antimicrobials. The aim of this study was to determine the prevalence of antimicrobial resistant (AMR) Salmonella spp and E. coli isolated from a sample of broiler farms in East Coast Malaysia from 2018-2019. A total of 384 cloacal swabs were collected from broilers farms in Kelantan, Terengganu, and Pahang. The bacteria were isolated and confirmed by bacteriological and serological methods. Following that, confirmed isolates were subjected to antimicrobial susceptibility test. Salmonella spp and E. coli were recovered from the cloacal swabs samples with the overall prevalence of 6.5% and 51.8% respectively. In Kelantan, Terengganu and Pahang, the prevalence of Salmonella spp were 7%, 6.5% and 5.8% respectively, while the prevalence for E. coli were 50%, 48.3% and 58% respectively. Salmonella spp and E. coli displayed resistance towards the following antimicrobials: erythromycin (100% for both pathogens), chloramphenicol (76.2%, 84.5%), tetracycline (62%, 94.6%), ampicillin (47.7%, 87%), sulfamethoxazole/trimethoprim (42.9%, 83.3%), ciprofloxacin (4.8%, 23.8%), nalidixic acid (9.6%, 60.7%), streptomycin (19%,66%), and kanamycin (28.6%,57%), cephalotin (0%, 11%), gentamicin (0%, 20.2%) respectively. No resistance were recorded towards colistin for both pathogens. Multidrug resistance (MDR) was recorded in 82% of Salmonella spp and 100% of E. coli. These findings demonstrate the high prevalence of MDR Salmonella spp. and E. coli in broiler farms in East coast Malaysia. This could be attributed to the excessive use of antimicrobial agents by the poultry farm owners. Enhanced control measures and a strong monitoring system should be urgently implemented to reduce the emergence of antimicrobial resistance that is harmful to public health.
Keywords
Antimicrobial resistance; Salmonella species; E.coli; Broiler chickens; Malaysia
Subject
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
