Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Opsoclonus-Myoclonus Syndrome, a Post-Infectious Neurologic Complication of COVID-19: Case Series and Review of Literature

Version 1 : Received: 12 December 2020 / Approved: 18 December 2020 / Online: 18 December 2020 (12:19:07 CET)

A peer-reviewed article of this Preprint also exists.

Emamikhah, M., Babadi, M., Mehrabani, M. et al. Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature. J. Neurovirol. (2021). https://doi.org/10.1007/s13365-020-00941-1Emamikhah, M., Babadi, M., Mehrabani, M. et al. Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature. J. Neurovirol. (2021). https://doi.org/10.1007/s13365-020-00941-1 Emamikhah, M., Babadi, M., Mehrabani, M. et al. Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature. J. Neurovirol. (2021). https://doi.org/10.1007/s13365-020-00941-1Emamikhah, M., Babadi, M., Mehrabani, M. et al. Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature. J. Neurovirol. (2021). https://doi.org/10.1007/s13365-020-00941-1

Journal reference: Journal of NeuroVirology 2021
DOI: 10.1007/s13365-020-00941-1

Abstract

Opsoclonus-myoclonus-ataxia syndrome is a heterogeneous constellation of symptoms ranging from full combination of these three neurological findings to varying degree of isolated individual sign. Since the emergence of coronavirus disease 2019 (COVID-19), neurological symptoms, syndromes and complications associated with this multi-organ viral infection have been reported and the various aspects of neurological involvement are increasingly uncovered. As a neuro-inflammatory disorder in nature, one would expect to observe opsoclonus-myoclonus syndrome after a prevalent viral infection in a pandemic scale, as it has been the case for many other neuro-inflammatory syndromes. We report seven cases of opsoclonus-myoclonus syndrome presumably para-infectious in nature and discuss their phenomenology, their possible pathophysiological relationship to COVID-19 and diagnostic and treatment strategy in each case. Finally we review the relevant data in the literature regarding the opsoclonus-myoclonus syndrome and possible similar cases associated with COVID-19 and its diagnostic importance for clinicians in various fields of medicine encountering COVID-19 patients and its complications.

Subject Areas

COVID-19; SARS-CoV-2; Opsoclonus; myoclonus; parainfectious

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.