Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

The Effectiveness of Therapeutic Physical Exercise in Patients with Amyotrophic Lateral Sclerosis in Relation to the Alsfrs-R Functionality Scale: A Systematic Review

Version 1 : Received: 20 November 2020 / Approved: 21 November 2020 / Online: 21 November 2020 (10:50:28 CET)

How to cite: Ortega-Hombrados, L.; Molina-Torres, G.; Galán-Mercant, A.; Sánchez- Guerrero, E.; González-Sánchez, M.; Ruiz-Muñoz, M. The Effectiveness of Therapeutic Physical Exercise in Patients with Amyotrophic Lateral Sclerosis in Relation to the Alsfrs-R Functionality Scale: A Systematic Review. Preprints 2020, 2020110555 (doi: 10.20944/preprints202011.0555.v1). Ortega-Hombrados, L.; Molina-Torres, G.; Galán-Mercant, A.; Sánchez- Guerrero, E.; González-Sánchez, M.; Ruiz-Muñoz, M. The Effectiveness of Therapeutic Physical Exercise in Patients with Amyotrophic Lateral Sclerosis in Relation to the Alsfrs-R Functionality Scale: A Systematic Review. Preprints 2020, 2020110555 (doi: 10.20944/preprints202011.0555.v1).

Abstract

What do you want to do ?New mailCopyBackground: to analyze the changes that a therapeutic physical exercise program is capable of causing in the functionality of patients suffering from ALS and in addition, to analyze the respiratory capacity. Methods: a systematic review of the PubMed, SCOPUS, Cochrane, SciELO, PEDro, CINAHL and MEDline databases is carried out. The information was filtered using the following MeSH terms: "Amyotrophic lateral sclerosis", "Physical Therapy", "Physical and Rehabilitation Medicine". Clinical trials published in the last 5 years were included in which one of the interventions was therapeutic physical exercise in patients with ALS, which included the ALSFRS-R as a result variable. Results: 10 clinical trials with a total of 421 patients were analyzed, of which 183 underwent rehabilitation with physical exercise and were part of the case group; the rest belong to the control group and their treatment was mostly passive. The observed trend is of a decrease of approximately 6 points in the ALSFRS-R scale at 6 months in the case groups; however, no behavior pattern was met in the controls. Conclusions: Therapeutic physical exercise could contribute to slow down the deterioration of the musculature of people with ALS, thus facilitating the performance of their daily activities.

Subject Areas

Amyotrophic lateral sclerosis; physical therapy; rehabilitation; exercise

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