Preprint Concept Paper Version 1 Preserved in Portico This version is not peer-reviewed

Tiny Earth: A Big Idea for STEM Education and Antibiotic Discovery

Version 1 : Received: 5 November 2020 / Approved: 6 November 2020 / Online: 6 November 2020 (16:50:46 CET)

How to cite: Hurley, A.; Chevrette, M.G.; Acharya, D.D.; Lozano, G.L.; Garavito, M.; Heinritz, J.; Balderrama, L.; Beebe, M.; DenHartog, M.L.; Corinaldi, K.; Engels, R.; Gutierrez, A.; Jona, O.; Putnam, J.H.I.; Rhodes, B.; Tsang, T.; Hernandez, S.; Bascom-Slack, C.; Blum, J.E.; Price, P.A.; Davis, D.; Klein, J.; Pultorak, J.; Sullivan, N.L.; Mouncey, N.J.; Dorrestein, P.C.; Miller, S.; Broderick, N.A.; Handelsman, J. Tiny Earth: A Big Idea for STEM Education and Antibiotic Discovery. Preprints 2020, 2020110250. https://doi.org/10.20944/preprints202011.0250.v1 Hurley, A.; Chevrette, M.G.; Acharya, D.D.; Lozano, G.L.; Garavito, M.; Heinritz, J.; Balderrama, L.; Beebe, M.; DenHartog, M.L.; Corinaldi, K.; Engels, R.; Gutierrez, A.; Jona, O.; Putnam, J.H.I.; Rhodes, B.; Tsang, T.; Hernandez, S.; Bascom-Slack, C.; Blum, J.E.; Price, P.A.; Davis, D.; Klein, J.; Pultorak, J.; Sullivan, N.L.; Mouncey, N.J.; Dorrestein, P.C.; Miller, S.; Broderick, N.A.; Handelsman, J. Tiny Earth: A Big Idea for STEM Education and Antibiotic Discovery. Preprints 2020, 2020110250. https://doi.org/10.20944/preprints202011.0250.v1

Abstract

The world faces two seemingly unrelated challenges—a shortfall in the STEM workforce and increasing antibiotic resistance among bacterial pathogens. We address these two challenges with Tiny Earth, an undergraduate research course that excites students about science and creates a pipeline for antibiotic discovery.

Keywords

antibiotic discovery; STEM education; biosynthetic gene cluster; molecular networking; multi-omics

Subject

Biology and Life Sciences, Biochemistry and Molecular Biology

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