Version 1
: Received: 5 November 2020 / Approved: 6 November 2020 / Online: 6 November 2020 (15:29:04 CET)
How to cite:
Abdelgader, A.Z.; Musa, L.M.A.; Tsubo, M.; El-Hag, F.M.; Saleem, A.O.; Kurosaki, Y.; Jawasreh, K.I.; Ahmed, M.A. Galway Point Mutation (FecXG) in the Bone Morphogenetic Protein 15 Gene (BMP15) Is Associated With Prolificacy in the Sudanese Desert Sheep Ecotypes. Preprints2020, 2020110246
Abdelgader, A.Z.; Musa, L.M.A.; Tsubo, M.; El-Hag, F.M.; Saleem, A.O.; Kurosaki, Y.; Jawasreh, K.I.; Ahmed, M.A. Galway Point Mutation (FecXG) in the Bone Morphogenetic Protein 15 Gene (BMP15) Is Associated With Prolificacy in the Sudanese Desert Sheep Ecotypes. Preprints 2020, 2020110246
Abdelgader, A.Z.; Musa, L.M.A.; Tsubo, M.; El-Hag, F.M.; Saleem, A.O.; Kurosaki, Y.; Jawasreh, K.I.; Ahmed, M.A. Galway Point Mutation (FecXG) in the Bone Morphogenetic Protein 15 Gene (BMP15) Is Associated With Prolificacy in the Sudanese Desert Sheep Ecotypes. Preprints2020, 2020110246
APA Style
Abdelgader, A.Z., Musa, L.M.A., Tsubo, M., El-Hag, F.M., Saleem, A.O., Kurosaki, Y., Jawasreh, K.I., & Ahmed, M.A. (2020). Galway Point Mutation (FecXG) in the Bone Morphogenetic Protein 15 Gene (BMP15) Is Associated With Prolificacy in the Sudanese Desert Sheep Ecotypes. Preprints. https://doi.org/
Chicago/Turabian Style
Abdelgader, A.Z., Khaleel I. Jawasreh and Mohammed-Khair A. Ahmed. 2020 "Galway Point Mutation (FecXG) in the Bone Morphogenetic Protein 15 Gene (BMP15) Is Associated With Prolificacy in the Sudanese Desert Sheep Ecotypes" Preprints. https://doi.org/
Abstract
This study tested the association between FecXG point mutation located in exon 2 of BMP15 gene and the prolificacy of Dubasi, Shugor and Watish sheep ecotypes, under dryland farming, Sudan. Blood samples were randomly collected from unrelated 100 ewes (Dubasi; n= 30, Shugor: n= 30, and Watish: n= 40). Bone Morphogenetic protein (BMP15) gene was amplified using PCR-RFLP. Two genotypes were found in all studied breeds (heterozygous and wild type). The calculated total genotype frequencies of BB, Bb and bb genotypes were 0.31, 0.69 and 0.00, respectively, while allele frequencies were 0.66 for B and 0.34 for b. Litter size was influenced by the genotypes of BMP15 gene, parities and subtypes (p<0.05), highest for Watish and 4th parity. Alignment of BMP15 samples along with database reference sequence revealed that most sequence regions were identical except for one variable nucleotide at position 111 bp where a guanine (G) was replaced by adenine (A) in Watish and Shugor samples. All amino acids were the same at residue 275. Watish and Shugor breeds are more related. The study concluded that the presence of one copy of FecXG point mutation of BMP15 gene increased the litter size by 0.17 lambs in the studied ecotypes.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
