Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Multidrug Resistant Escherichia coli Harboring Extended-spectrum β-lactamase-encoding Genes Isolated from Clinically-healthy Pigs

Version 1 : Received: 19 September 2020 / Approved: 21 September 2020 / Online: 21 September 2020 (04:26:52 CEST)

How to cite: Lay, K.K.; Torio, H.E.; Bitrus, A.A.; Mala, W.; Nuananong, S.; Chuanchuen, R. Multidrug Resistant Escherichia coli Harboring Extended-spectrum β-lactamase-encoding Genes Isolated from Clinically-healthy Pigs. Preprints 2020, 2020090494 (doi: 10.20944/preprints202009.0494.v1). Lay, K.K.; Torio, H.E.; Bitrus, A.A.; Mala, W.; Nuananong, S.; Chuanchuen, R. Multidrug Resistant Escherichia coli Harboring Extended-spectrum β-lactamase-encoding Genes Isolated from Clinically-healthy Pigs. Preprints 2020, 2020090494 (doi: 10.20944/preprints202009.0494.v1).

Abstract

Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli is a serious-global public health issue. A total of 292 E. coli isolates obtained from fecal samples of pigs in Central (n = 103) and Northeastern (n = 189) provinces of Thailand were included in this study. Eighty-six E. coli isolates were phenotypically confirmed to be β-lactamase producers (29.5%) and screened for the presence of β-lactamase genes. The genes in CTX-M family was most frequently found (90.7%). The blaCTX-M-15 gene (59.3%) was predominantly identified CTX-M genotype, followed by blaCTX-M-14 (31.4%) and blaCTX-M-4 (25.6%). The blaTEM-1 gene was prevalent (75.6%). The blaCTX-M-4 and blaCTX-M-14 genes were located on conjugative plasmid. The results highlight healthy pigs as reservoirs of ESBL-producing E. coli carrying ESBL genes that could be horizontally transferred.

Subject Areas

ESBL; Escherichia coli; Pigs; Thailand

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.