Lay, K. K.; Torio, H. E.; Bitrus, A. A.; Mala, W.; Nuananong, S.; Chuanchuen, R. Multidrug Resistant Escherichia coli Harboring Extended-spectrum β-lactamase-encoding Genes Isolated from Clinically-healthy Pigs. Preprints2020, 2020090494. https://doi.org/10.20944/preprints202009.0494.v1
APA Style
Lay, K. K., Torio, H. E., Bitrus, A. A., Mala, W., Nuananong, S., & Chuanchuen, R. (2020). Multidrug Resistant <em>Escherichia</em><em> coli</em> Harboring Extended-spectrum β-lactamase-encoding Genes Isolated from Clinically-healthy Pigs. Preprints. https://doi.org/10.20944/preprints202009.0494.v1
Chicago/Turabian Style
Lay, K. K., Sinwat Nuananong and Rungtip Chuanchuen. 2020 "Multidrug Resistant <em>Escherichia</em><em> coli</em> Harboring Extended-spectrum β-lactamase-encoding Genes Isolated from Clinically-healthy Pigs" Preprints. https://doi.org/10.20944/preprints202009.0494.v1
Abstract
Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli is a serious-global public health issue. A total of 292 E. coli isolates obtained from fecal samples of pigs in Central (n = 103) and Northeastern (n = 189) provinces of Thailand were included in this study. Eighty-six E. coli isolates were phenotypically confirmed to be β-lactamase producers (29.5%) and screened for the presence of β-lactamase genes. The genes in CTX-M family was most frequently found (90.7%). The blaCTX-M-15 gene (59.3%) was predominantly identified CTX-M genotype, followed by blaCTX-M-14 (31.4%) and blaCTX-M-4 (25.6%). The blaTEM-1 gene was prevalent (75.6%). The blaCTX-M-4 and blaCTX-M-14 genes were located on conjugative plasmid. The results highlight healthy pigs as reservoirs of ESBL-producing E. coli carrying ESBL genes that could be horizontally transferred.
Keywords
ESBL; Escherichia coli; Pigs; Thailand
Subject
Biology and Life Sciences, Immunology and Microbiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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