Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Effects of Gender and Obesity on Daytime Sleepiness in Obstructive Sleep Apnoea Patients

Version 1 : Received: 15 September 2020 / Approved: 16 September 2020 / Online: 16 September 2020 (07:19:33 CEST)

How to cite: Sah, S.K.; Tan, H.Z.; Yu, S.; Feng, J.; Zhang, Y.H.; Shah, A.K. Effects of Gender and Obesity on Daytime Sleepiness in Obstructive Sleep Apnoea Patients. Preprints 2020, 2020090354 (doi: 10.20944/preprints202009.0354.v1). Sah, S.K.; Tan, H.Z.; Yu, S.; Feng, J.; Zhang, Y.H.; Shah, A.K. Effects of Gender and Obesity on Daytime Sleepiness in Obstructive Sleep Apnoea Patients. Preprints 2020, 2020090354 (doi: 10.20944/preprints202009.0354.v1).

Abstract

Objective: Identify factors associated with excessive day time sleepiness (EDS) in individuals with obstructive sleep apnea (OSA), and analyze the effects that obesity and gender have on excessive daytime sleepiness in such individuals. Methods: A total of 160 people were selected for this study. All the people have completed a clinical evaluation, and whose apnea-hypopnea index (AHI) > 10 events/hour of sleep on polysomnography were included in the study from the Department of otolaryngology. Results: The Mean age was 43.87±11.34 years, mean EDS score was 14.09± 4.91, and mean AHI was 43.88±20.66 events/hour of sleep. Male presented lower mean age, higher EDS scores, and more time in apnoea, whereas females presented with higher mean age, lower EDS scores, and less time in sleep apnea. The EDS score showed best correlation with duration of apnoea (r = 0.448; p < 0.01), peripheral oxygen saturation (SpO2; r = -0.458; p < 0.01) and AHI (r = 0.484; p < 0.01). The mean body mass index (BMI) was 27.41±3.86 kg/m2. Normal, Overweight, obese, and morbidly obese were observed in 20%, 61%, 18%, and 0.6% of cases, respectively. Severity of the disease best correlated with BMI (r = 0.421; p < 0.01). Conclusions: OSA is predominant in males (M/F 5:1), and obese population. Females diagnosed with OSA have higher mean age. However, EDS scores and time spent in sleep apnoea is lower in females. Higher BMI is associated with EDS, irrespective of gender.

Subject Areas

sleep apnoea; obstructive sleep apnoea; polysomnography; excessive day time sleepiness; obesity

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