Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Evaluation of Column Test Methods to Study Inactivation of Chemically Bonded Silica Gels

Version 1 : Received: 1 September 2020 / Approved: 3 September 2020 / Online: 3 September 2020 (11:41:25 CEST)

How to cite: Hanai, T. Evaluation of Column Test Methods to Study Inactivation of Chemically Bonded Silica Gels. Preprints 2020, 2020090070 (doi: 10.20944/preprints202009.0070.v1). Hanai, T. Evaluation of Column Test Methods to Study Inactivation of Chemically Bonded Silica Gels. Preprints 2020, 2020090070 (doi: 10.20944/preprints202009.0070.v1).

Abstract

The silanol activity and trace metal detection methods for chemically bonded silica gels were evaluated in silico. Test compounds with large molecular sizes may demonstrate negative results because of the possibility of indirect hydrogen bonding via short alkyl groups or siloxane of the silica gels. This hypothesis was based on the observation of weak hydrogen bonding energy values similar to those observed in the study of the alkyl group effect on the hydrogen bonding of alkanols. Consequently, smaller molecules may be a better choice for the analysis of bonded-phase quality.

Subject Areas

inactivation column test; silanol; trace metals; in silico; bonded-phase silica

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.