Version 1
: Received: 1 September 2020 / Approved: 3 September 2020 / Online: 3 September 2020 (04:43:08 CEST)
How to cite:
Baenas, N.; Ruales, J.; Moreno, D.A.; Barrio, D.A.; Stinco, C.M.; Martínez-Cifuentes, G.; Meléndez-Martínez, A.J.; García-Ruiz, A. Characterization of Andean Blueberry in Bioactive Compounds, Evaluation of Biological Properties and in vitro Bioaccessibility. Preprints2020, 2020090055 (doi: 10.20944/preprints202009.0055.v1).
Baenas, N.; Ruales, J.; Moreno, D.A.; Barrio, D.A.; Stinco, C.M.; Martínez-Cifuentes, G.; Meléndez-Martínez, A.J.; García-Ruiz, A. Characterization of Andean Blueberry in Bioactive Compounds, Evaluation of Biological Properties and in vitro Bioaccessibility. Preprints 2020, 2020090055 (doi: 10.20944/preprints202009.0055.v1).
Cite as:
Baenas, N.; Ruales, J.; Moreno, D.A.; Barrio, D.A.; Stinco, C.M.; Martínez-Cifuentes, G.; Meléndez-Martínez, A.J.; García-Ruiz, A. Characterization of Andean Blueberry in Bioactive Compounds, Evaluation of Biological Properties and in vitro Bioaccessibility. Preprints2020, 2020090055 (doi: 10.20944/preprints202009.0055.v1).
Baenas, N.; Ruales, J.; Moreno, D.A.; Barrio, D.A.; Stinco, C.M.; Martínez-Cifuentes, G.; Meléndez-Martínez, A.J.; García-Ruiz, A. Characterization of Andean Blueberry in Bioactive Compounds, Evaluation of Biological Properties and in vitro Bioaccessibility. Preprints 2020, 2020090055 (doi: 10.20944/preprints202009.0055.v1).
Abstract
Andean blueberries are wild berries grown and consumed in Ecuador which contain high values of bioactive compounds, mainly anthocyanins, with powerful antioxidant activity. The aim of this study was to evaluate the profile and contents of (poly)phenols and carotenoids in Andean blueberry by HPLC-DAD-MSn and determine a wide range of its biological activities. The antioxidant capacity of this fruit was evaluated in vitro by three different methods and in vivo using the zebrafish animal model, also the toxicity effect was determined by the zebrafish embryogenesis test. Besides, the antimicrobial activity and the capacity of Andean blueberry to produce hemagglutination in blood cells were evaluated. Finally, the bioaccessibility of (poly)phenols and related antioxidant capacity were determined in the different phases of an in vitro digestion. The global results indicated no toxicity of Andean blueberry, weakly bacteriostatic activity, and high contents of anthocyanins and antioxidant capacity, which were partially bioaccesible in vitro (~ 50 % at the final intestinal step), contributing to the knowledge of its health benefits for consumers and its potential use in the food and pharmaceutical industry as functional ingredient.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Nieves Baenas
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