Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Neurobrucellosis with Gait disturbance: A Neurological Case Report

Version 1 : Received: 16 August 2020 / Approved: 19 August 2020 / Online: 19 August 2020 (08:41:47 CEST)

How to cite: Mehrabi, S.; Shahriari, E.; Afrakhteh, M.; Ranjbar, M.; Zeinlai, M.; Haghi Ashtiani, B. Neurobrucellosis with Gait disturbance: A Neurological Case Report. Preprints 2020, 2020080404 (doi: 10.20944/preprints202008.0404.v1). Mehrabi, S.; Shahriari, E.; Afrakhteh, M.; Ranjbar, M.; Zeinlai, M.; Haghi Ashtiani, B. Neurobrucellosis with Gait disturbance: A Neurological Case Report. Preprints 2020, 2020080404 (doi: 10.20944/preprints202008.0404.v1).

Abstract

Brucellosis is a multi-system infectious disease that exhibits with various manifestations and complications. Neurobrucellosis is a rare but serious presentation of brucellosis that can be discovered in every stages of the disease. Laboratory tests and physical examination and patient history are generally the basis for diagnosing the disease. It has both insidious and prolonged clinical course of the disease and long-term therapies. Also the most common pattern of exhibition is subacute or chronic. We reported a case of young female who had history of painless weakness in the right lower limb (proximal and distal) that started gradually and had progressed over the time, and after a month she felt weakness in the left lower limb with the same pattern. Lumbosacral Magnetic resonance imaging (MRI) with and without contrast was shown evidence of enhancement thickening of caudal equina ventral roots. Brucella antigen titer was positive, the result was 1/160. And other clinical tests were normal. Patient treated with Intravenous injection (IV) Rifampicin and Intravenous Cotrimoxazole. patient was discharged with good health and continuinng all two medications for 5 months. The descision was taken to report this case as a result of entire respond in patient’s illness after a enduring disease. Neurobrucellosis is a treatable disease in which it would be better to consider a high indication of suspicion. Due to if ignored, it may cause significant morbidity and mortality.

Subject Areas

neurobrucellosis; gait disturbance; flaccid paraprasia; weakness

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