Working Paper Article Version 1 This version is not peer-reviewed

Towards An App to Estimate Patient-specific Perioperative Femur Fracture Risk

Version 1 : Received: 22 July 2020 / Approved: 23 July 2020 / Online: 23 July 2020 (09:41:30 CEST)

A peer-reviewed article of this Preprint also exists.

Esposito, L.; Minutolo, V.; Gargiulo, P.; Jonsson, H., Jr.; Gislason, M.K.; Fraldi, M. Towards an App to Estimate Patient-Specific Perioperative Femur Fracture Risk. Appl. Sci. 2020, 10, 6409. Esposito, L.; Minutolo, V.; Gargiulo, P.; Jonsson, H., Jr.; Gislason, M.K.; Fraldi, M. Towards an App to Estimate Patient-Specific Perioperative Femur Fracture Risk. Appl. Sci. 2020, 10, 6409.

Journal reference: Appl. Sci. 2020, 10, 6409
DOI: 10.3390/app10186409

Abstract

Total Hip Arthroplasty is one of the most successful surgery. However, due to the worldwide growing population life expectancy and the related incidence of age-dependent bone diseases, a growing number of cases of intra-operative fractures lead to revision surgery with high rates of morbidity and mortality. Surgeons choose the type of the implant, either cemented or cementless prosthesis, on the basis of the age, the quality of the bone and the general medical conditions of the patients. Generally, no quantitative measures are available to assess the intra-operative fracture risk. Consequently, the decision-making process is mainly based on medical operators’ expertise and qualitative information obtained by imaging. Motivated by this scenario, we here propose a mechanical-supported strategy to assist surgeons in their decisions, by giving intelligible maps of the risk fracture which take into account the interplay between actual strength distribution inside the bone tissue and its response to the forces exerted by the implant. To this end, we produce charts and patient-specific synthetic “traffic-light” indicators of fracture risk, by making use of ad hoc analytical solutions to predict the stress levels in the bone by means of CT-based mechanical and geometrical parameters of the patient. We felt that, if implemented in a friendly software or proposed as an app, the strategy could constitute a practical tool to help the medical decision-making process, in particular with respect to the choice of adopting cemented or cementless implant

Subject Areas

total hip arthroplasty; intra-operative femur fracture risk; bone elastic-plastic behavior

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