Preprint Case Report Version 1 This version is not peer-reviewed

Linezolid Add-On Rescue Therapy Cured MRSA Necrotizing Pneumonia: A Case Report in a Preterm Infant

Version 1 : Received: 9 July 2020 / Approved: 11 July 2020 / Online: 11 July 2020 (02:10:45 CEST)

How to cite: Al-Omran, A.M.; Al-Abdi, S.Y.; Al-Amer, H.M. Linezolid Add-On Rescue Therapy Cured MRSA Necrotizing Pneumonia: A Case Report in a Preterm Infant. Preprints 2020, 2020070219 (doi: 10.20944/preprints202007.0219.v1). Al-Omran, A.M.; Al-Abdi, S.Y.; Al-Amer, H.M. Linezolid Add-On Rescue Therapy Cured MRSA Necrotizing Pneumonia: A Case Report in a Preterm Infant. Preprints 2020, 2020070219 (doi: 10.20944/preprints202007.0219.v1).

Abstract

Necrotizing pneumonia due to Methicillin-Resistant Staphylococcus Aureus (MRSA) is devastating and difficult to treat in preterm infants. We report a case of severe MRSA necrotizing pneumonia in a preterm infant. As an add-on rescue therapy to vancomycin, linezolid rapidly cured this case after the failure of vancomycin plus rifampicin. This rapid cure suggests that adjunctive rather than rescue linezolid may be considered in such cases.

Subject Areas

Preterm infant; Necrotizing pneumonia; Methicillin-Resistant Staphylococcus Aureus (MRSA); Pneumatoceles; Linezolid; Vancomycin; Rifampicin

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