Preprint Article Version 2 Preserved in Portico This version is not peer-reviewed

Routine Use of Feeding Jejunostomy in Pancreaticoduodenectomy: A Metaanalysis

Version 1 : Received: 7 June 2020 / Approved: 9 June 2020 / Online: 9 June 2020 (04:09:43 CEST)
Version 2 : Received: 3 September 2020 / Approved: 5 September 2020 / Online: 5 September 2020 (06:33:29 CEST)

How to cite: Vasavada, B.; Patel, H. Routine Use of Feeding Jejunostomy in Pancreaticoduodenectomy: A Metaanalysis. Preprints 2020, 2020060114 (doi: 10.20944/preprints202006.0114.v2). Vasavada, B.; Patel, H. Routine Use of Feeding Jejunostomy in Pancreaticoduodenectomy: A Metaanalysis. Preprints 2020, 2020060114 (doi: 10.20944/preprints202006.0114.v2).

Abstract

Aims and objectives: The primary aim of our study was to evaluate morbidity and mortality following feeding jejunostomy in pancreaticoduodenectomy compared to the control group. We also evaluated individual complications like delayed gastric emptying; post operative pancreatic fistula, superficial and deep surgical site infection. Material and Methods: The study was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and MOOSE guidelines. Heterogeneity was measured using Q tests and I2.the random-effects model was used. Results: Four studies including Total of 1639 patients were included in the analysis. Total 843 patients were included in Feeding jejunostomy group and 796 patients included in control group without feeding jejunostomy. Over all morbidity was significantly higher in feeding jejunostomy group. (P = 0.001). There was no significant difference between both the groups. (P=0.07). Delayed gastric emptying was significantly higher in feeding jejunostomy group. [P=0.021]. There was no significant difference in development of pancreatic fistula between the two groups. Deep surgical site infection was significantly higher in feeding jejunostomy group. (P=0.013). Hospital stay was significantly more in feeding jejunostomy group (p<0.0001). There was no significant difference between readmission; TPN requirement and time to start oral feed. Conclusion: Feeding jejunostomy seems to be associated with increased morbidity and increased length of stay.

Subject Areas

Pancreaticoduodenectomy; feeding jejunostomy; morbidity; mortality

Comments (1)

Comment 1
Received: 5 September 2020
Commenter: BHAVIN Vasavada
Commenter's Conflict of Interests: Author
Comment: we have added few limitations and updated figures for better understanding of the article
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