Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Surgical Outcomes of Transvaginal Neobladder-Vaginal Fistula Repair after Radical Cystectomy with Ileal Orthotopic Neobladder

Version 1 : Received: 20 May 2020 / Approved: 21 May 2020 / Online: 21 May 2020 (09:32:33 CEST)

How to cite: Song, W.; Lee, D.H. Surgical Outcomes of Transvaginal Neobladder-Vaginal Fistula Repair after Radical Cystectomy with Ileal Orthotopic Neobladder. Preprints 2020, 2020050339 (doi: 10.20944/preprints202005.0339.v1). Song, W.; Lee, D.H. Surgical Outcomes of Transvaginal Neobladder-Vaginal Fistula Repair after Radical Cystectomy with Ileal Orthotopic Neobladder. Preprints 2020, 2020050339 (doi: 10.20944/preprints202005.0339.v1).

Abstract

To present surgical methods and outcomes of neobladder-vaginal fistula (NVF) repair after radical cystectomy (RC) with ileal orthotopic neobladder (IONB). Methods: We retrospectively reviewed 136 women who underwent RC with IONB for bladder cancer between January 2010 and December 2018. The NVF was confirmed by cystoscopy and/or voiding cystography. NVF repair was performed using a transvaginal approach, which included circumferential incision of the fistula tract, creation of a plane between the neobladder serosa and the vaginal epithelium, and multi-layered transvaginal closure. Results: During a median follow-up of 47.9 months, NVF was identified in 12 (8.8%) women. Eight fistulas were located in the proximal anterior vaginal wall and four in the vaginal apex. Median time from RC to NVF repair was 3.4 months. Median NVF size and duration of urethral Foley catheter indwelling was 6.0 mm and 24.0 days, respectively. Initial repair of NVF was successful in ten (83.3%) patients. Two (16.7%) patients who relapsed retained IONB through the subsequent operation. Two (16.7%) patients developed urinary incontinence after NVF repair, requiring anti-incontinence surgery. Conclusions: The transvaginal approach for NVF repair is feasible, yielding successful surgical outcomes. However, women should be counseled about the risks of relapse and urinary incontinence.

Subject Areas

Neobladder-vaginal fistula; Orthotopic urinary diversion; Radical cystectomy; Surgical outcomes; Vaginal approach

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