Submitted:
18 April 2020
Posted:
19 April 2020
You are already at the latest version
Preprints on COVID-19 and SARS-CoV-2
Abstract
The outbreak of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) has caused severe damage to the world. With the support of classic evolutionary theories and population genetics principles, many studies on the origin of SARS-CoV-2 have revealed encouraging results but meanwhile are still under debate. We are concerned with the validity of applying classic evolutionary theories and formula to the evolution of RNA viruses. We have raised several factors like the RNA replication feature and the RNA modification systems of the hosts, which might jeopardize the validity of the application of classic methods to analyze the SARS-CoV-2 data.
Keywords:
SARS-CoV-2
; evolution and origin
; RNA virus
; application
; concerns
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