Version 1
: Received: 14 April 2020 / Approved: 16 April 2020 / Online: 16 April 2020 (16:05:27 CEST)
How to cite:
Raj, S.; Chandel, V.; Rathi, B.; Kumar, D. Understanding the Molecular Mechanism(s) of SARS-CoV2 Infection and Propagation in Human to Discover Potential Preventive and Therapeutic Approach. Preprints2020, 2020040285 (doi: 10.20944/preprints202004.0285.v1).
Raj, S.; Chandel, V.; Rathi, B.; Kumar, D. Understanding the Molecular Mechanism(s) of SARS-CoV2 Infection and Propagation in Human to Discover Potential Preventive and Therapeutic Approach. Preprints 2020, 2020040285 (doi: 10.20944/preprints202004.0285.v1).
Cite as:
Raj, S.; Chandel, V.; Rathi, B.; Kumar, D. Understanding the Molecular Mechanism(s) of SARS-CoV2 Infection and Propagation in Human to Discover Potential Preventive and Therapeutic Approach. Preprints2020, 2020040285 (doi: 10.20944/preprints202004.0285.v1).
Raj, S.; Chandel, V.; Rathi, B.; Kumar, D. Understanding the Molecular Mechanism(s) of SARS-CoV2 Infection and Propagation in Human to Discover Potential Preventive and Therapeutic Approach. Preprints 2020, 2020040285 (doi: 10.20944/preprints202004.0285.v1).
Abstract
In December 2019, outbreak of novel coronavirus (COVID-19) occurred in Wuhan, Hubei Province, China and exported across the world leading to thousands of deaths and millions of suspected cases. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection into the host undergoes a huge number of complex replicative machineries which still remains unclear. Understanding the mechanism (s) of replication and mode of infection of SARS-CoV2 to human cells will help us in the development of novel vaccines or drugs for the eradication and prevention of the disease. This review compiles the knowledge of SARS-CoV2 replicative machinery, mode of infection to the human cells and the development of drugs and vaccines which are currently under clinical trials.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
