Working Paper Review Version 1 This version is not peer-reviewed

A Spoonful of Honey Helps Antibiotic Usage Go Down

Version 1 : Received: 28 October 2019 / Approved: 29 October 2019 / Online: 29 October 2019 (10:45:51 CET)

A peer-reviewed article of this Preprint also exists.

Nolan, V.C.; Harrison, J.; Cox, J.A.G. Dissecting the Antimicrobial Composition of Honey. Antibiotics 2019, 8, 251. Nolan, V.C.; Harrison, J.; Cox, J.A.G. Dissecting the Antimicrobial Composition of Honey. Antibiotics 2019, 8, 251.

Abstract

Honey is a complex sweet food stuff with well-established antimicrobial and antioxidant properties. It has been used for millennia in a variety of applications, but those most noteworthy include treatment of surface wounds, burns and inflammation. A variety of substances in honey have been suggested as the key component to its antimicrobial potential; polyphenolic compounds, hydrogen peroxide, methylglyoxal and bee-defensin 1. These components vary greatly across honey samples due to botanical origin, geographical location and the individual bee. The use of medical grade honey, Medihoney and Revamil, in the treatment of surface wounds and burns has been seen to improve the healing process, reduce healing time, reduce scarring and prevent microbial contamination. Therefore, medical grade honeys should be used for these treatments and reduce the demand for antibiotic usage. In this review, we aim to outline the constituents of honey and how they affect the antibiotic potential of honeys in a clinical setting.

Keywords

honey; antimicrobials; methylglyoxal; hydrogen peroxide; bee-defensin 1; wound treatment

Subject

Biology and Life Sciences, Immunology and Microbiology

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