Version 1
: Received: 23 August 2019 / Approved: 26 August 2019 / Online: 26 August 2019 (16:04:26 CEST)
How to cite:
Simdi, E.; Ozcan, K. The Literature Review of Electricity Effects on Cell Physiology and Related New Electrical Treatment Modalities. Preprints.org2019, 2019080274. https://doi.org/10.20944/preprints201908.0274.v1
Simdi, E.; Ozcan, K. The Literature Review of Electricity Effects on Cell Physiology and Related New Electrical Treatment Modalities. Preprints.org 2019, 2019080274. https://doi.org/10.20944/preprints201908.0274.v1
Cite as:
Simdi, E.; Ozcan, K. The Literature Review of Electricity Effects on Cell Physiology and Related New Electrical Treatment Modalities. Preprints.org2019, 2019080274. https://doi.org/10.20944/preprints201908.0274.v1
Simdi, E.; Ozcan, K. The Literature Review of Electricity Effects on Cell Physiology and Related New Electrical Treatment Modalities. Preprints.org 2019, 2019080274. https://doi.org/10.20944/preprints201908.0274.v1
Abstract
This paper is a mini literature review about electromagnetic field’s effects on cells, tissues and new treatment modalities. We have reviewed a papers which have been published in high quality journals in the last 5 years as two authors. This review’s aim is to be a resource for experimental studies about electricity’s effects on cell biology and pathophysiology. As a result of this literature review, we found that especially extremely low electric frequency and intermediate frequency fields have very important pathophysiological effects. We have mentioned four important expressions on this subject; electroporation, electrofusion, electrochemotherapy, gene electrotransference. Two different new treatment approaches have been developed by use of these two important electrical waves. First is tumor treating fields and the other is pulsed electric fields. Most studies in literature have been done with extremely low frequency and pulsed electric fields. In terms of diseases, most studies are about glioblastoma multiforme and malign melanoma.Most studies in literature have been done with extremely low frequency and pulsed electric fields. In terms of diseases, most studies are about glioblastoma and melanoma.
Keywords
electricity; tumor treating fields; extremely low frequency; pulsed electric fields; new cancer treatment modalities; glioblastoma; electroporation; electrofusion; electrochemotherapy; gene electrotransference
Subject
Biology and Life Sciences, Anatomy and Physiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.