Preprint Article Version 1 This version is not peer-reviewed

2DE-pattern: A Database for Inventory of Human Proteoforms

Version 1 : Received: 28 June 2019 / Approved: 4 July 2019 / Online: 4 July 2019 (10:29:30 CEST)

How to cite: Naryzhny, S.; Klopov, N.; Ronzhina, N.; Zorina, E.; Zgoda, V.; Kleyst, O.; Belyakova, N.; Legina, O. 2DE-pattern: A Database for Inventory of Human Proteoforms. Preprints 2019, 2019070074 (doi: 10.20944/preprints201907.0074.v1). Naryzhny, S.; Klopov, N.; Ronzhina, N.; Zorina, E.; Zgoda, V.; Kleyst, O.; Belyakova, N.; Legina, O. 2DE-pattern: A Database for Inventory of Human Proteoforms. Preprints 2019, 2019070074 (doi: 10.20944/preprints201907.0074.v1).

Abstract

The human proteome is composed from diverse and heterogeneous gene products/proteoforms. Previously, we have been discussing the main technical aspects in developing for inventory of human proteoforms that would be visually attractive, clear, and easy to search (Naryzhny S. J. Proteomics 2018, S1874-3919(18) 30220-3). Here, we present our first draft of the database of proteoforms that is based on this discussion. The database principles and structure are described. The database is called “2DE-pattern” as it contains multiple isoform-centric patterns of proteoforms separated according to 2DE principles.

Subject Areas

proteoforms; database; bioinformatics; pattern; 2DE

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