2DE-pattern: A Database for Inventory of Human Proteoforms

Stanislav Naryzhny; Nikolay Klopov; Natalia Ronzhina; Elena Zorina; Victor Zgoda; Olga Kleyst; Natalia Belyakova; Olga Legina

doi:10.20944/preprints201907.0074.v1

Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 28 June 2019 / Approved: 4 July 2019 / Online: 4 July 2019 (10:29:30 CEST)

The human proteome is composed from diverse and heterogeneous gene products/proteoforms. Previously, we have been discussing the main technical aspects in developing for inventory of human proteoforms that would be visually attractive, clear, and easy to search (Naryzhny S. J. Proteomics 2018, S1874-3919(18) 30220-3). Here, we present our first draft of the database of proteoforms that is based on this discussion. The database principles and structure are described. The database is called “2DE-pattern” as it contains multiple isoform-centric patterns of proteoforms separated according to 2DE principles.

proteoforms; database; bioinformatics; pattern; 2DE

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2DE-pattern: A Database for Inventory of Human Proteoforms

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