preprints.org > environmental and earth sciences > space and planetary science > doi: 10.20944/preprints201906.0120.v2

Preprint Article Version 2 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 7 June 2019 / Approved: 14 June 2019 / Online: 14 June 2019 (14:57:44 CEST)
Version 2 : Received: 1 July 2019 / Approved: 2 July 2019 / Online: 2 July 2019 (11:28:36 CEST)

After astrochemistry and astrobiology, astrotoxicology is a further subfield of astroscience. Astrotoxicology is an interdisciplinary science that combines physics, biology, chemistry, astronomy, medicine and toxicology. Unlike toxicology on Earth, astrotoxicology in space must take into account the specific features of extreme conditions such as gravity, radiation, temperature or pressure and also consider the distinctions of extreme conditions on other celestial bodies. The field of action of astrotoxicology is, therefore, the influence of lower gravity on the toxicological characteristics of substances in the human body, the special dangers caused by increased radiation in space and on other planets and the special chemical changes caused by the extreme conditions in space on substances and the toxicological consequences associated with them. Despite growing space research, there are so far only a few pharmacokinetic, pharmacodynamic or toxicological investigations under conditions of microgravity and knowledge of toxicology under the extreme conditions in space in particular. Future studies will be the beginning of astrotoxicology, a previously unknown branch of toxicology.

astrotoxicology, astrobiology, astrochemistry, mars, manned space flight, microgravitation, radiation

Environmental and Earth Sciences, Space and Planetary Science

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