Tiwari, P.K.; Rai, N.K.; Kumar, R.; Parigger, C.G.; Rai, A.K. Atomic and Molecular Laser-Induced Breakdown Spectroscopy of Selected Pharmaceuticals. Atoms2019, 7, 71.
Tiwari, P.K.; Rai, N.K.; Kumar, R.; Parigger, C.G.; Rai, A.K. Atomic and Molecular Laser-Induced Breakdown Spectroscopy of Selected Pharmaceuticals. Atoms 2019, 7, 71.
Tiwari, P.K.; Rai, N.K.; Kumar, R.; Parigger, C.G.; Rai, A.K. Atomic and Molecular Laser-Induced Breakdown Spectroscopy of Selected Pharmaceuticals. Atoms2019, 7, 71.
Tiwari, P.K.; Rai, N.K.; Kumar, R.; Parigger, C.G.; Rai, A.K. Atomic and Molecular Laser-Induced Breakdown Spectroscopy of Selected Pharmaceuticals. Atoms 2019, 7, 71.
Abstract
Laser-induced breakdown spectroscopy (LIBS) of pharmaceutical drugs that contain paracetamol is investigated in air and argon atmospheres. Characteristic neutral and ionic spectral lines of various elements and molecular signatures of CN violet and C2 Swan band systems are observed. The relative hardness of all drug samples is measured as well. Principal component analysis, a multivariate method, is applied in data analysis for demarcation purposes of the drug samples. The CN violet and C2 Swan spectral radiances are investigated for evaluation of possible correlation of the chemical and molecular structures of the pharmaceuticals. Complementary Raman and Fourier-transform-infra-red spectroscopies are used record molecular spectra of the drug samples. The applicationof the above techniques for the drug screening are important for identification and mitigation of drugs that reveal additives that may cause adverse side-effects.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received:
23 July 2020
Commenter:
Dr Pravin Kumar Tiwari
The commenter has declared there is no conflict of interests.
Comment:
This article is peer-reviewed and its review were also mentioned at the journal website but unfortunately, it is mentioned here that this article is not peer-reviewed. Maybe this is showing because it was uploaded before the final decision on the article by the editor. Please correct your self.
Commenter: Dr Pravin Kumar Tiwari
The commenter has declared there is no conflict of interests.