Article
Version 1
Preserved in Portico This version is not peer-reviewed
Wearable Enzymatic Alcohol Biosensor
Version 1
: Received: 4 April 2019 / Approved: 8 April 2019 / Online: 8 April 2019 (15:07:30 CEST)
A peer-reviewed article of this Preprint also exists.
Lansdorp, B.; Ramsay, W.; Hamidand, R.; Strenk, E. Wearable Enzymatic Alcohol Biosensor. Sensors 2019, 19, 2380. Lansdorp, B.; Ramsay, W.; Hamidand, R.; Strenk, E. Wearable Enzymatic Alcohol Biosensor. Sensors 2019, 19, 2380.
Abstract
Transdermal alcohol biosensors have the ability to detect the alcohol that emanates from the bloodstream and diffuses through the skin. However, they have suffered from long-term fouling of the sensor element and drift in the resulting sensor readings over time. Here, we report a disposable cartridge platform that solves the problem of sensor fouling, and an enzymatic detection pathway that minimizes baseline drift for sensitive detection. Laboratory characterization of the enzymatic alcohol sensor demonstrates a linear sensor range of between 0 and 50 mM. Further, we show continuous transdermal alcohol data recorded with a human subject over 48 hours.
Keywords
alcohol; biosensor; cartridge; disposable; transdermal; Alcohol Use Disorder
Subject
Chemistry and Materials Science, Analytical Chemistry
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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