Version 1
: Received: 5 March 2019 / Approved: 6 March 2019 / Online: 6 March 2019 (13:33:08 CET)
How to cite:
Mochel, J. A Review of Relevant Therapeutic Targets for the Management of Congestive Heart Failure in Dogs: Present and Future Directions. Preprints2019, 2019030082. https://doi.org/10.20944/preprints201903.0082.v1
Mochel, J. A Review of Relevant Therapeutic Targets for the Management of Congestive Heart Failure in Dogs: Present and Future Directions. Preprints 2019, 2019030082. https://doi.org/10.20944/preprints201903.0082.v1
Mochel, J. A Review of Relevant Therapeutic Targets for the Management of Congestive Heart Failure in Dogs: Present and Future Directions. Preprints2019, 2019030082. https://doi.org/10.20944/preprints201903.0082.v1
APA Style
Mochel, J. (2019). <strong>A Review of Relevant Therapeutic Targets for the Management of Congestive Heart Failure in Dogs: Present and Future Directions</strong>. Preprints. https://doi.org/10.20944/preprints201903.0082.v1
Chicago/Turabian Style
Mochel, J. 2019 "<strong>A Review of Relevant Therapeutic Targets for the Management of Congestive Heart Failure in Dogs: Present and Future Directions</strong>" Preprints. https://doi.org/10.20944/preprints201903.0082.v1
Abstract
Congestive heart failure (CHF) is a major cause of morbidity and mortality with an increasing prevalence in human and canine populations. Similar to humans, overactivation of the renin-angiotensin aldosterone system is involved in the pathophysiology of CHF in dogs. Current therapeutic strategies for the management of canine CHF include the use of RAAS inhibitors, diuretics and inodilators. The present review summarizes data from our own research on the modulation of the renin-angiotensin cascade in dogs in dogs, together with new findings (including novel therapeutic targets) from the veterinary and the human literature.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
