Preprint Review Version 1 This version is not peer-reviewed

3D Printing Applied to Tissue Engineered Blood Grafts

Version 1 : Received: 22 November 2018 / Approved: 26 November 2018 / Online: 26 November 2018 (11:39:44 CET)

A peer-reviewed article of this Preprint also exists.

Wenger, R.; Giraud, M.-N. 3D Printing Applied to Tissue Engineered Vascular Grafts. Appl. Sci. 2018, 8, 2631. Wenger, R.; Giraud, M.-N. 3D Printing Applied to Tissue Engineered Vascular Grafts. Appl. Sci. 2018, 8, 2631.

Journal reference: Appl. Sci. 2018, 8, 2631
DOI: 10.3390/app8122631

Abstract

Abstract: The broad clinical use of synthetic vascular grafts for vascular diseases is limited by their thrombogenicity and low patency rate, especially for vessels with a diameter inferior to 6 mm. Alternatives such as tissue-engineered blood grafts (TEBGs) have gained increasing interest. Among the different manufacturing approaches, 3D bioprinting presents numerous advantages and enables the fabrication of multi-scale, multi-material, and multicellular tissues with heterogeneous and functional intrinsic structures. Extrusion-, inkjet- and light-based 3D printing techniques have been used for the fabrication of TEBG out of hydrogels, cells, and/or solid polymers. This review discusses the state-of-the-art research on the use of 3D printing for TEBG with a focus on the biomaterials and deposition methods.

Subject Areas

3D printing; Bioprinting; Additive Manufacturing, Tissue Engineering, Blood Vessels, Vascular Grafting

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