Chai, Y.; Jing, L.; Xiuli, S.; Zhenkun, L.; Lirong, Z.; Guocun, H. Phase Angle Associated with Over-Hydration in Healthy Chinese. Preprints2018, 2018110567. https://doi.org/10.20944/preprints201811.0567.v1
APA Style
Chai, Y., Jing, L., Xiuli, S., Zhenkun, L., Lirong, Z., & Guocun, H. (2018). <strong><em></em></strong>Phase Angle Associated with Over-Hydration in Healthy Chinese. Preprints. https://doi.org/10.20944/preprints201811.0567.v1
Chicago/Turabian Style
Chai, Y., Zhang Lirong and Hou Guocun. 2018 "<strong><em></em></strong>Phase Angle Associated with Over-Hydration in Healthy Chinese" Preprints. https://doi.org/10.20944/preprints201811.0567.v1
Abstract
Background A body composition monitor (BCM) has a role not only in determining over-hydration (OH) but also as an aid to nutritional assessment. For dialysis patient-specific clinical applications of BCM, it is necessary to clarify the relationship between body composition parameters and OH in healthy Chinese individuals. Methods This cross-sectional study involved 314 healthy individuals with a mean age of 45.7±13.1 years. BCM measurements were performed while the subjects were fasting. Results The mean OH level was 0.379±0.81 L. Lean tissue index (LTI) and Lean tissue mass (LTM) were significantly higher in males (p<0.001), while fat tissue index (FTI) was significantly higher in females (p<0.001). In univariate correlation analysis, FTI, Fat, and ATM had a negative correlation with OH in females and all subjects (p<0.05), while LTM and BCM had a positive correlation in all subjects (p<0.05). There was a significant negative correlation between phase angle (PhA) and OH in males, females, and all subjects (r=-0.634, p<0.001; r=-0.666, p<0.001; r=-0.484, p<0.001, respectively). In multivariate linear regression analysis, PhA (b=-1.266, p<0.001), LTM (b=0.987, p<0.001), age (b=-0.307, p<0.001) were independent predictors of OH. Conclusions This study demonstrated that age, LTM and especially PhA, had important roles in predicting OH in healthy Chinese individuals. In the future, PhA may aid in clinical assessment by helping to titrate dry weight among hemodialysis patients with malnutrition.
Keywords
bio-impedance, phase angle, over-hydration, body composition, nutrition, hemodialysis
Subject
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
