Mustafin, Z.S.; Zamyatin, V.I.; Konstantinov, D.K.; Doroshkov, A.V.; Lashin, S.A.; Afonnikov, D.A. Phylostratigraphic Analysis Shows the Earliest Origination of the Abiotic Stress Associated Genes in A. thaliana. Genes2019, 10, 963.
Mustafin, Z.S.; Zamyatin, V.I.; Konstantinov, D.K.; Doroshkov, A.V.; Lashin, S.A.; Afonnikov, D.A. Phylostratigraphic Analysis Shows the Earliest Origination of the Abiotic Stress Associated Genes in A. thaliana. Genes 2019, 10, 963.
Mustafin, Z.S.; Zamyatin, V.I.; Konstantinov, D.K.; Doroshkov, A.V.; Lashin, S.A.; Afonnikov, D.A. Phylostratigraphic Analysis Shows the Earliest Origination of the Abiotic Stress Associated Genes in A. thaliana. Genes2019, 10, 963.
Mustafin, Z.S.; Zamyatin, V.I.; Konstantinov, D.K.; Doroshkov, A.V.; Lashin, S.A.; Afonnikov, D.A. Phylostratigraphic Analysis Shows the Earliest Origination of the Abiotic Stress Associated Genes in A. thaliana. Genes 2019, 10, 963.
Abstract
Phylostratigraphic analysis is a way to look anew on phylogenetic data in the evolutionary aspect. It allows counting the evolutionary age based on the analysis of genes, their orthologs and finding the last common ancestor. We performed phylostratigraphic analysis of Arabidopsis thaliana genes associated with several types of abiotic stresses (heat, cold, water-related, light, osmotic, salt, and oxidative) determined by the Gene Ontology annotation. Comparison of the distributions of ages of genes associated with stresses of different type has shown the heat stress to involve older genes while the light stress – younger genes. At the same time, all types of stress are characterized by a significantly higher proportion of old genes (common to all eukaryotes) compared to the whole set of A.thaliana genes. This can be explained by the involvement of basic molecular processes in plant cells into the stress response. Reconstruction and graphical analysis of the gene network of the heat stress educed several clusters associated with different response functions. Some of these clusters contain only ancient genes. The results obtained show that the phylostratigraphic analysis reveals the fundamental features of the organization of gene networks and their evolution.
Keywords
gene network; network analysis; transcription regulation network; Cytoscape; gene family evolution; divergence; A. thaliana; abiotic stress
Subject
Biology and Life Sciences, Plant Sciences
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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