Version 1
: Received: 13 November 2018 / Approved: 15 November 2018 / Online: 15 November 2018 (08:37:05 CET)
How to cite:
Idowu, P.A.; Mpayipheli, M.; Muchenje, V. Can Mannose-Binding Lectin Activation Help in Fighting Bacterial Pathogen in Poultry Production Systems?—A Review. Preprints2018, 2018110350. https://doi.org/10.20944/preprints201811.0350.v1
Idowu, P.A.; Mpayipheli, M.; Muchenje, V. Can Mannose-Binding Lectin Activation Help in Fighting Bacterial Pathogen in Poultry Production Systems?—A Review. Preprints 2018, 2018110350. https://doi.org/10.20944/preprints201811.0350.v1
Idowu, P.A.; Mpayipheli, M.; Muchenje, V. Can Mannose-Binding Lectin Activation Help in Fighting Bacterial Pathogen in Poultry Production Systems?—A Review. Preprints2018, 2018110350. https://doi.org/10.20944/preprints201811.0350.v1
APA Style
Idowu, P.A., Mpayipheli, M., & Muchenje, V. (2018). Can Mannose-Binding Lectin Activation Help in Fighting Bacterial Pathogen in Poultry Production Systems?—A Review. Preprints. https://doi.org/10.20944/preprints201811.0350.v1
Chicago/Turabian Style
Idowu, P.A., Maliviwe Mpayipheli and Voster Muchenje. 2018 "Can Mannose-Binding Lectin Activation Help in Fighting Bacterial Pathogen in Poultry Production Systems?—A Review" Preprints. https://doi.org/10.20944/preprints201811.0350.v1
Abstract
Bacterial pathogens have been attributed to poultry housing structure, financial strength, and incessant use of antibiotics, variable seasons and management systems practiced. Variant forms of bacterial pathogens can be detected by recognizing the molecular pattern of the pathogens through an innate immune mechanism such as mannose-binding lectin. Mannose-binding lectin (MBL) possesses an innate pattern recognition molecule that easily sequestered to region of infections and inflammations. This works by attaching itself to antigen surface thus hinders proliferation and disease activity in the host organism. Baker’s method, nephelometric assays technique, Enzyme-Linked Immunosurbent Assay technique, Polymerase Chain Reaction, Deoxyribonucleic Acid typing and other biotechnology related methods are techniques used in detecting and quantifying MBL. Mannose-binding lectin levels in serum can be influenced by age, management systems, feed formulation strategies and seasons. Therefore, knowledge of MBL should be encouraged in all aspect of poultry production, in order to discourage incessant use of drugs at a slight exposure to prevailing bacterial which can help in maximizing cost.
Keywords
mannose-binding lectin; poultry; production system; pathogens; innate immune response
Subject
Biology and Life Sciences, Immunology and Microbiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
