Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Lipid Membrane Based Biosensors

Version 1 : Received: 8 October 2018 / Approved: 9 October 2018 / Online: 9 October 2018 (05:59:30 CEST)

A peer-reviewed article of this Preprint also exists.

Nikoleli, G.-P.; Nikolelis, D.P.; Siontorou, C.G.; Nikolelis, M.-T.; Karapetis, S. The Application of Lipid Membranes in Biosensing. Membranes 2018, 8, 108. Nikoleli, G.-P.; Nikolelis, D.P.; Siontorou, C.G.; Nikolelis, M.-T.; Karapetis, S. The Application of Lipid Membranes in Biosensing. Membranes 2018, 8, 108.

Abstract

The exploitation of lipid membranes in biosensors has provided the ability to reconstitute a considerable part of their functionality to detect trace of food toxicants and environmental pollutants. Nanotechnology enabled sensor miniaturization and extended the range of biological moieties that could be immobilized within a lipid bilayer device. This chapter reviews recent progress in biosensor technologies based on lipid membranes suitable for environmental applications and food quality monitoring. Numerous biosensing applications are presented, putting emphasis on novel systems, new sensing techniques and nanotechnology-based transduction schemes. The range of analytes that can be currently detected include, insecticides, pesticides, herbicides, metals, toxins, antibiotics, microorganisms, hormones, dioxins, etc. Technology limitations and future prospects are discussed, focused on the evaluation/ validation and eventually commercialization of the proposed sensors.

Keywords

biosensors; enzyme-based systems; receptor-based systems; toxins; food analysis; environmental monitoring; nanotechnology

Subject

Chemistry and Materials Science, Analytical Chemistry

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