Version 1
: Received: 13 September 2018 / Approved: 18 September 2018 / Online: 18 September 2018 (11:53:28 CEST)
How to cite:
Sun, Y.; Liu, J.; Sun, J.; Huang, Y.; Lu, J.; Li, M.; Jin, N.; Dai, X.; Fan, B. One-Pot Synthesis of Coumarins Unsubstituted on the Pyranic Nucleus Catalysed by a Wells–Dawson Heteropolyacid (H6P2W18O62). Preprints2018, 2018090349. https://doi.org/10.20944/preprints201809.0349.v1
Sun, Y.; Liu, J.; Sun, J.; Huang, Y.; Lu, J.; Li, M.; Jin, N.; Dai, X.; Fan, B. One-Pot Synthesis of Coumarins Unsubstituted on the Pyranic Nucleus Catalysed by a Wells–Dawson Heteropolyacid (H6P2W18O62). Preprints 2018, 2018090349. https://doi.org/10.20944/preprints201809.0349.v1
Sun, Y.; Liu, J.; Sun, J.; Huang, Y.; Lu, J.; Li, M.; Jin, N.; Dai, X.; Fan, B. One-Pot Synthesis of Coumarins Unsubstituted on the Pyranic Nucleus Catalysed by a Wells–Dawson Heteropolyacid (H6P2W18O62). Preprints2018, 2018090349. https://doi.org/10.20944/preprints201809.0349.v1
APA Style
Sun, Y., Liu, J., Sun, J., Huang, Y., Lu, J., Li, M., Jin, N., Dai, X., & Fan, B. (2018). One-Pot Synthesis of Coumarins Unsubstituted on the Pyranic Nucleus Catalysed by a Wells–Dawson Heteropolyacid (H<sub>6</sub>P<sub>2</sub>W<sub>18</sub>O<sub>62</sub>). Preprints. https://doi.org/10.20944/preprints201809.0349.v1
Chicago/Turabian Style
Sun, Y., Xiao-Feng Dai and Bei Fan. 2018 "One-Pot Synthesis of Coumarins Unsubstituted on the Pyranic Nucleus Catalysed by a Wells–Dawson Heteropolyacid (H<sub>6</sub>P<sub>2</sub>W<sub>18</sub>O<sub>62</sub>)" Preprints. https://doi.org/10.20944/preprints201809.0349.v1
Abstract
The development of a method to produce coumarins unsubstituted on the pyranic nucleus catalyzed from Wells–Dawson heteropolyacid (H6P2W18O62), phenol derivatives and ethyl 3,3-diethoxypropionate using Pechmann condensation under solvent-free conditions is described. This catalytic method was also applied successfully to synthesize various substituted coumarins, including the corresponding phenols and ethyl 3,3-diethoxypropionate. This work provides a novel, cheaper and safer way to syhthesize coumarins unsubstituted on the pyranic nucleus.
Chemistry and Materials Science, Organic Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
