Version 1
: Received: 4 September 2018 / Approved: 5 September 2018 / Online: 5 September 2018 (01:35:46 CEST)
How to cite:
Gambogou, B.; Ouattara, A.K.; Taale, E.; Karou, S.D.; Ameyapoh, Y.A.; Simpore, J. Garlic as Alternative Therapy to Treat Uropathogene Bacteria in Women with Urinary Tract Infection in Lomé, Togo. Preprints2018, 2018090077. https://doi.org/10.20944/preprints201809.0077.v1
Gambogou, B.; Ouattara, A.K.; Taale, E.; Karou, S.D.; Ameyapoh, Y.A.; Simpore, J. Garlic as Alternative Therapy to Treat Uropathogene Bacteria in Women with Urinary Tract Infection in Lomé, Togo. Preprints 2018, 2018090077. https://doi.org/10.20944/preprints201809.0077.v1
Gambogou, B.; Ouattara, A.K.; Taale, E.; Karou, S.D.; Ameyapoh, Y.A.; Simpore, J. Garlic as Alternative Therapy to Treat Uropathogene Bacteria in Women with Urinary Tract Infection in Lomé, Togo. Preprints2018, 2018090077. https://doi.org/10.20944/preprints201809.0077.v1
APA Style
Gambogou, B., Ouattara, A.K., Taale, E., Karou, S.D., Ameyapoh, Y.A., & Simpore, J. (2018). Garlic as Alternative Therapy to Treat Uropathogene Bacteria in Women with Urinary Tract Infection in Lomé, Togo. Preprints. https://doi.org/10.20944/preprints201809.0077.v1
Chicago/Turabian Style
Gambogou, B., Yaovi A. Ameyapoh and Jacques Simpore. 2018 "Garlic as Alternative Therapy to Treat Uropathogene Bacteria in Women with Urinary Tract Infection in Lomé, Togo" Preprints. https://doi.org/10.20944/preprints201809.0077.v1
Abstract
The urinary tract infection (UTI) is the most common bacterial infection, especially in women. The increased incidence of UTIs, at the last decades have paralleled with the growing emergence of antibiotic resistance. The aim is to evaluate aqueous garlic extract (AGE) susceptibility against multidrug-resistant (MDR) bacteria isolated in urine of women. The investigation of antibacterial propriety and time kill effect of AGE was performed by the well method, microdilution method and spectrophotometer assay. Antibiotics susceptibility assay revealed that the nine MDR bacteria had high resistance against Amoxicillin/ clavulanic acid (100%) and Erythromycin (100%), Cefotaxime (83.33%) and Ceftazidime (83.33%). AGE exhibited potent antibacterial activity against the nine MDR bacteria tested. In Gram-negative bacteria, the inhibition diameters ranged from 20 ± 3 to 32 ± 4 mm, with Minimum Inhibitory Concentrations (MICs) ranging from 10% to 12.5% (w/v) and Minimum Bactericidal Concentration (MBCs) was 12.5 % (w/v). Gram-positive bacteria exhibited diameters ranging from 38 ± 2 to 45 ± 1 mm; MIC and MBC values ranged from 05 to 10 % (w/v) and were found more susceptible than Gram-negative bacteria. To conclude, this investigation shown that AGE have high potential antibacterial to use as an alternative to treat women UTIs.
Keywords
Garlic, Antibiotics, Lomé, Uropathogenic bacteria, Urinary Tract Infection, Multidrug resistance and alternative therapy.
Subject
Biology and Life Sciences, Immunology and Microbiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
