Review
Version 1
Preserved in Portico This version is not peer-reviewed
Non-Human Primate Models of Enteric Viral Infections
Version 1
: Received: 24 August 2018 / Approved: 27 August 2018 / Online: 27 August 2018 (00:17:27 CEST)
A peer-reviewed article of this Preprint also exists.
Sestak, K. Non-Human Primate Models of Enteric Viral Infections. Viruses 2018, 10, 544. Sestak, K. Non-Human Primate Models of Enteric Viral Infections. Viruses 2018, 10, 544.
Abstract
There is an important role non-human primates (NHP) play in biomedical research. Phylogenetic proximity of any of the NHP species to Homo sapiens assures that much better translatability of research outcomes from model studies involving human diseases can be achieved than from those generated with other pre-clinical systems. Our group and others used during past two decades NHPs in research directed towards viral and autoimmune disorders of the gastrointestinal tract. This review summarizes progress made in the area of enteric viral infections and its applicability to human disease.
Keywords
Enteric Virus, Non-Human Primate, Virome, Macaque, Dysbiosis, Enteritis, Diarrhea, Animal Model, Rotavirus, Calicivirus, Gut Microbiome
Subject
Biology and Life Sciences, Virology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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