Lai, C.-C.; Chou, W.; Cheng, A.-C.; Chao, C.-M.; Cheng, K.-C.; Ho, C.-H.; Chen, C.-M. The Effect of Early Cardiopulmonary Rehabilitation on the Outcomes of Intensive Care Unit Survivors. Medicine 2019, 98, e14877, doi:10.1097/md.0000000000014877.
Lai, C.-C.; Chou, W.; Cheng, A.-C.; Chao, C.-M.; Cheng, K.-C.; Ho, C.-H.; Chen, C.-M. The Effect of Early Cardiopulmonary Rehabilitation on the Outcomes of Intensive Care Unit Survivors. Medicine 2019, 98, e14877, doi:10.1097/md.0000000000014877.
Lai, C.-C.; Chou, W.; Cheng, A.-C.; Chao, C.-M.; Cheng, K.-C.; Ho, C.-H.; Chen, C.-M. The Effect of Early Cardiopulmonary Rehabilitation on the Outcomes of Intensive Care Unit Survivors. Medicine 2019, 98, e14877, doi:10.1097/md.0000000000014877.
Lai, C.-C.; Chou, W.; Cheng, A.-C.; Chao, C.-M.; Cheng, K.-C.; Ho, C.-H.; Chen, C.-M. The Effect of Early Cardiopulmonary Rehabilitation on the Outcomes of Intensive Care Unit Survivors. Medicine 2019, 98, e14877, doi:10.1097/md.0000000000014877.
Abstract
Background: This study aims to compare the impact of early and late post-discharge cardiopulmonary rehabilitation on the outcomes of intensive care unit (ICU) survivors. Methods: The retrospective, cohort study used a sub-database of the Taiwan National Health Insurance Research Database (NHIRD) that contains information of all patients had ICU admission between 2000 and 2012. Early group was defined if patients had received cardiopulmonary rehabilitation within 30 days after ICU discharge, and late group was define as if patients had received cardiopulmonary rehabilitation between 30 days and one year after ICU discharge. The end points were mortality and re-admission during the 3-year follow-up. Results: Among 2136 patients received cardiopulmonary rehabilitation after ICU discharge, 994 was classified early group and other 1142 patients were classified as late group. Overall, early group had a lower mortality rate (6.64% vs 10.86%, p = 0.0006), and a lower ICU readmission rate (47.8% vs 57.97%, p < 0.0001) than late group after 3-year follow-up. Kaplan-Meier analysis showed that early group had significantly lower mortality (p=0.0009) and readmission rate (p<0.0001) than late group. In multivariate analysis, the risk of ICU readmission was found to be independently associated with late group (HR, 1.28; 95% CI, 1.13-1.47). Conclusions: Early post-discharge cardiopulmonary rehabilitation among ICU survivors has the long-term survival benefit and significantly decreases the readmission rate.
Keywords
Intensive care unit, early cardiopulmonary rehabilitation, mortality, readmission
Subject
Physical Sciences, Applied Physics
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
