Version 1
: Received: 30 July 2018 / Approved: 30 July 2018 / Online: 30 July 2018 (15:41:48 CEST)
How to cite:
Luthjens, L.; Yao, T.; Warman, J. A Polymer-Gel Eye-Phantom for 3D Fluorescent Imaging of Millimetre Radiation Beams. Preprints2018, 2018070597. https://doi.org/10.20944/preprints201807.0597.v1
Luthjens, L.; Yao, T.; Warman, J. A Polymer-Gel Eye-Phantom for 3D Fluorescent Imaging of Millimetre Radiation Beams. Preprints 2018, 2018070597. https://doi.org/10.20944/preprints201807.0597.v1
Luthjens, L.; Yao, T.; Warman, J. A Polymer-Gel Eye-Phantom for 3D Fluorescent Imaging of Millimetre Radiation Beams. Preprints2018, 2018070597. https://doi.org/10.20944/preprints201807.0597.v1
APA Style
Luthjens, L., Yao, T., & Warman, J. (2018). A Polymer-Gel Eye-Phantom for 3D Fluorescent Imaging of Millimetre Radiation Beams. Preprints. https://doi.org/10.20944/preprints201807.0597.v1
Chicago/Turabian Style
Luthjens, L., Tiantian Yao and John Warman. 2018 "A Polymer-Gel Eye-Phantom for 3D Fluorescent Imaging of Millimetre Radiation Beams" Preprints. https://doi.org/10.20944/preprints201807.0597.v1
Abstract
Abstract: We have filled a 24 mm diameter glass sphere with a transparent polymer-gel that is radio-fluorogenic, i.e. it becomes (permanently) fluorescent when irradiated, with an intensity proportional to the local dose deposited. The gel consists of >99.9% tertiary-butyl acrylate (TBA) pre-polymerized to ~15% conversion, and ~100 ppm maleimido-pyrene (MPy). Its dimensions and physical properties are close to those of the vitreous body of the human eye. We have irradiated the gel with a 3 mm diameter, 200 kVp X-ray beam with a dose rate of ~1 Gy/min. A 3D (video) view of the beam within the gel has been constructed from tomographic images obtained by scanning the sample through a thin sheet of UV light. To minimize optical artifacts, the cell was immersed in a square tank containing a refractive-index-matching medium. The 20%-80% penumbra of the beam was determined to be ~0.4 mm. The research was a preparatory investigation of the possibility of using the method to monitor the millimetre diameter proton pencil beams used in ocular radiotherapy.
Keywords
Keywords: Radiotherapy eye-phantom; radio-fluorogenic gel; x-ray beam imaging; 3D radiation imaging; polymer gel dosimetry.
Subject
Chemistry and Materials Science, Polymers and Plastics
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
