Preprint Article Version 1 This version is not peer-reviewed

A Polymer-Gel Eye-Phantom for 3D Fluorescent Imaging of Millimetre Radiation Beams

Version 1 : Received: 30 July 2018 / Approved: 30 July 2018 / Online: 30 July 2018 (15:41:48 CEST)

How to cite: Luthjens, L.; Yao, T.; Warman, J. A Polymer-Gel Eye-Phantom for 3D Fluorescent Imaging of Millimetre Radiation Beams. Preprints 2018, 2018070597 (doi: 10.20944/preprints201807.0597.v1). Luthjens, L.; Yao, T.; Warman, J. A Polymer-Gel Eye-Phantom for 3D Fluorescent Imaging of Millimetre Radiation Beams. Preprints 2018, 2018070597 (doi: 10.20944/preprints201807.0597.v1).

Abstract

Abstract: We have filled a 24 mm diameter glass sphere with a transparent polymer-gel that is radio-fluorogenic, i.e. it becomes (permanently) fluorescent when irradiated, with an intensity proportional to the local dose deposited. The gel consists of >99.9% tertiary-butyl acrylate (TBA) pre-polymerized to ~15% conversion, and ~100 ppm maleimido-pyrene (MPy). Its dimensions and physical properties are close to those of the vitreous body of the human eye. We have irradiated the gel with a 3 mm diameter, 200 kVp X-ray beam with a dose rate of ~1 Gy/min. A 3D (video) view of the beam within the gel has been constructed from tomographic images obtained by scanning the sample through a thin sheet of UV light. To minimize optical artifacts, the cell was immersed in a square tank containing a refractive-index-matching medium. The 20%-80% penumbra of the beam was determined to be ~0.4 mm. The research was a preparatory investigation of the possibility of using the method to monitor the millimetre diameter proton pencil beams used in ocular radiotherapy.

Subject Areas

Keywords: Radiotherapy eye-phantom; radio-fluorogenic gel; x-ray beam imaging; 3D radiation imaging; polymer gel dosimetry.

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