Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Biofilm removal and bacterial re-colonization inhibition of a novel erythritol/chlorhexidine air-polishing powder on titanium disks.

Version 1 : Received: 23 July 2018 / Approved: 23 July 2018 / Online: 23 July 2018 (12:41:42 CEST)

A peer-reviewed article of this Preprint also exists.

Mensi, M.; Cochis, A.; Sordillo, A.; Uberti, F.; Rimondini, L. Biofilm Removal and Bacterial Re-Colonization Inhibition of a Novel Erythritol/Chlorhexidine Air-Polishing Powder on Titanium Disks. Materials 2018, 11, 1510. Mensi, M.; Cochis, A.; Sordillo, A.; Uberti, F.; Rimondini, L. Biofilm Removal and Bacterial Re-Colonization Inhibition of a Novel Erythritol/Chlorhexidine Air-Polishing Powder on Titanium Disks. Materials 2018, 11, 1510.

Abstract

Abstract: Air-polishing with low abrasiveness powders is fats arising as a valid and mini-invasive instrument for the management of biofilm colonizing dental implants. The reported advantage is the efficient removal of plaque with respect of the titanium integrity. In the present study, we evaluated the in-situ plaque-removal and continual the post-treatment anti-bacterial efficacy of an innovative erythritol/chlorhexidine air-polishing powder and compared it with sodium bicarbonate. Two peri-implantitis-linked biofilm formers strains Staphylococcus aureus and Aggregatibacter actinomycetemcomitans were selected and used to infect titanium disks before and after the air-polishing treatment. Cells number and viability were assayed by colonies forming units (CFUs) count and metabolic-colorimetric (2,3-Bis-(2-Methoxy-4-Nitro-5-Sulfophenyl)-2H-Tetrazolium-5-Carboxanilide) (XTT) assay. Air-polishing performed with either sodium bicarbonate or erythritol/chlorhexidine was effective in reducing bacteria biofilm viability and number onto pre-infected specimens, while erythritol/ chlorhexidine showed a higher post-treatment biofilm re-growth inhibition. Surface analysis via mechanical profilometry failed to show an increase in titanium roughness, regardless of the powder selected.

Keywords

air-polishing; titanium; erythritol; chlorhexidine; biofilm; implants;

Subject

Medicine and Pharmacology, Dentistry and Oral Surgery

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