Version 1
: Received: 1 June 2018 / Approved: 4 June 2018 / Online: 4 June 2018 (10:41:51 CEST)
How to cite:
Chanphai, P.; Tajmir-Riahi, H. Functionalized Folic Acid-Chitosan Nanoparticles for Encapsulation of Dietary Polyphenols. Preprints2018, 2018060033. https://doi.org/10.20944/preprints201806.0033.v1
Chanphai, P.; Tajmir-Riahi, H. Functionalized Folic Acid-Chitosan Nanoparticles for Encapsulation of Dietary Polyphenols. Preprints 2018, 2018060033. https://doi.org/10.20944/preprints201806.0033.v1
Chanphai, P.; Tajmir-Riahi, H. Functionalized Folic Acid-Chitosan Nanoparticles for Encapsulation of Dietary Polyphenols. Preprints2018, 2018060033. https://doi.org/10.20944/preprints201806.0033.v1
APA Style
Chanphai, P., & Tajmir-Riahi, H. (2018). Functionalized Folic Acid-Chitosan Nanoparticles for Encapsulation of Dietary Polyphenols. Preprints. https://doi.org/10.20944/preprints201806.0033.v1
Chicago/Turabian Style
Chanphai, P. and H.A. Tajmir-Riahi. 2018 "Functionalized Folic Acid-Chitosan Nanoparticles for Encapsulation of Dietary Polyphenols" Preprints. https://doi.org/10.20944/preprints201806.0033.v1
Abstract
Encapsulation of antioxidant polyphenols leads to increase solubility and bioavailability of these micronutrients in solution. The encapsulation of antioxidant resveratrol, genistein and curcumin by folic acid-chitosan nanocapsules was studied in aqueous solution, using multiple spectroscopic methods, TEM images. Structural analysis showed that polyphenol bindings are via hydrophilic, hydrophobic and H-bonding contacts with resveratrol forming more stable conjugates. As chitosan size increased, the binding efficacy and stability of polyphenol-polymer adducts were increased. Polyphenol binding induced major alterations of chitosan morphology. Chitosan nanoparticles are capable of delivery of polyphenols in vitro.
Keywords
polyphenols; folic acid-chitosan; encapsulation; loading efficacy; TEM
Subject
Biology and Life Sciences, Food Science and Technology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
