Aptamer-based Biosensors for Antibiotic Detection: A Review

Asol Mehlhorn; Parvaneh Rahimi; Yvonne Joseph

doi:10.20944/preprints201804.0343.v2

Preprint Review Version 2 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 26 April 2018 / Approved: 26 April 2018 / Online: 26 April 2018 (16:51:27 CEST)
Version 2 : Received: 27 April 2018 / Approved: 27 April 2018 / Online: 27 April 2018 (16:11:09 CEST)

Antibiotic resistance and accordingly their pollution because of uncontrolled usage has emerged as a serious problem in recent years. Hence, there is an increased demand to develope robust, easy, and sensitive methods for rapid evaluation of antibiotic and their residues. Among different analytical methods, the aptamer-based biosensors (aptasensors) have attracted considerable attention because of good selectivity, specificity, and sensitivity. This review gives an overview about recent developed aptasensors for antibiotic detection. The use of various aptamer assays to determine different groups of antibiotics like β-lactams, Aminoglycosides, Anthracyclines, Chloramphenicol, (Fluoro)Quinolones, Lincosamide, Tetracyclines and Sulfonamides are presented in this paper.

biosensor; aptasensor; aptamer; antibiotic; ampicillin; penicillin; gentamicin; kanamycin; neomycin; tobramycin; streptomycin; daunomycin; chloramphenicol; ciprofloxacin; danofloxacin; enrofloxacin; ofloxacin; lincomycin; oxytetracycline; tetracycline; sulfadimethoxine

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Aptamer-based Biosensors for Antibiotic Detection: A Review

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