Aptamer-based Biosensors for Antibiotic Detection: A Review

Asol Mehlhorn; Parvaneh Rahimi; Yvonne Joseph

doi:10.20944/preprints201804.0343.v2

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preprints.org > chemistry and materials science > analytical chemistry > doi: 10.20944/preprints201804.0343.v2

Preprint Review Version 2 Preserved in Portico This version is not peer-reviewed

Aptamer-based Biosensors for Antibiotic Detection: A Review

Asol Mehlhorn

Parvaneh Rahimi

^* ,

Yvonne Joseph

Version 1 : Received: 26 April 2018 / Approved: 26 April 2018 / Online: 26 April 2018 (16:51:27 CEST)
Version 2 : Received: 27 April 2018 / Approved: 27 April 2018 / Online: 27 April 2018 (16:11:09 CEST)

A peer-reviewed article of this Preprint also exists.

Mehlhorn, A.; Rahimi, P.; Joseph, Y. Aptamer-Based Biosensors for Antibiotic Detection: A Review. Biosensors 2018, 8, 54. Mehlhorn, A.; Rahimi, P.; Joseph, Y. Aptamer-Based Biosensors for Antibiotic Detection: A Review. Biosensors 2018, 8, 54.

DOI: 10.3390/bios8020054

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Abstract

Antibiotic resistance and accordingly their pollution because of uncontrolled usage has emerged as a serious problem in recent years. Hence, there is an increased demand to develope robust, easy, and sensitive methods for rapid evaluation of antibiotic and their residues. Among different analytical methods, the aptamer-based biosensors (aptasensors) have attracted considerable attention because of good selectivity, specificity, and sensitivity. This review gives an overview about recent developed aptasensors for antibiotic detection. The use of various aptamer assays to determine different groups of antibiotics like β-lactams, Aminoglycosides, Anthracyclines, Chloramphenicol, (Fluoro)Quinolones, Lincosamide, Tetracyclines and Sulfonamides are presented in this paper.

Keywords

biosensor; aptasensor; aptamer; antibiotic; ampicillin; penicillin; gentamicin; kanamycin; neomycin; tobramycin; streptomycin; daunomycin; chloramphenicol; ciprofloxacin; danofloxacin; enrofloxacin; ofloxacin; lincomycin; oxytetracycline; tetracycline; sulfadimethoxine

Subject

Chemistry and Materials Science, Analytical Chemistry

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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